BACKGROUND Resuscitation after cardiac arrest (CA) with a whole-body ischemia-reperfusion injury causes brain injury and multiple organ dysfunction (MODS). This study aimed to determine whether mild systemic hypothermia could decrease multiple organ dysfunctions after resuscitation from cardiac arrest. METHODS The patients who had been resuscitated after cardiac arrest were reviewed. During t...

Approximately 40 trillion bacteria reside inside the human intestine, meaning there are at least as many cells of microbial origin as human origin [1]. While it was once believed that bacteria and humans simply coexisted in the same space, a wide body of evidence now suggests that host–microbial communication is more complex than ever imagined and the microbiome plays a critical role in maintai...

BACKGROUND Multiple organ dysfunction (MOD) has plagued intensive care units (ICUs) for more than four decades, and its epidemiology has evolved because more patients are surviving previously lethal insults. Over the years, different predominant phenotypes of MOD have been described, all of which have consumed tremendous healthcare resources and have been associated with prolonged ICU stays and...

From the Academic Unit of Anaesthesia and Intensive Care, School of Medicine, University of Aberdeen AB25 2ZD, UK (Drs. Noha El Sakka, Helen F. Galley and Nigel R. Webster), Department of Clinical Pathology, Faculty of Medicine, University of Alexandria, Egypt (Drs. Ola Sharaki, Myriam Helmy, Salah Marzouk and Mona Sedrak), and Department of Anaesthesia, Faculty of Medicine, University of Alexa...

The formation of myocardial dysfunction in neonatal sepsis remains a topical issue current practice. Myocardial with is found to promote double increase loss rate, and maintenance an adequate cardiac output very important predictor for survival patients sepsis. Purpose - study clinico-paraclinical markers case alternative term debut timely verification rational correction cardiovascular disorde...