OBJECTIVES Few studies investigated the isolation of stem cells from pathologically injured dental tissues. The aim of this study was to assess the possibility of isolation of stem cells from pulp polyps (chronic hyperplastic pulpitis), a pathological tissue produced in an inflammatory proliferative response within a tooth. STUDY DESIGN Pulp polyp tissues were enzymatically digested and the h...

introduction calcifying odontogenic cyst (coc) is an uncommon odontogenic lesion, classified in two variants: the cystic variant and neoplastic (solid) variant. case presentation this case report presents multiple coc, which involved the maxillary bone and sinus in a 30-year-old man. several of these lesions were cystic, while the others were neoplastic in type, and the lesions were removed sur...

Calcifying odontogenic cyst is a developmental odontogenic cyst first described by Gorlin in 1962. It is considered as an extremely rare condition and shows extensive diversity in its clinicopathological appearances and biologic behavior. In this report a rare case of calcifying odontogenic cyst with ameloblastic proliferation (an extremely rare histologic variant) with one year follow – up is ...

background: limited resources for adult stem cells necessitate their in vitro culture prior to clinical use. investigating mitochondrial dna (mtdna) and telomere shortening has proved to be important indications of stem cell validity. this study was designed to investigate these indicators in multiple passages of three adult stem cell lines which were produced in our stem cell laboratory. metho...

To examine the roles of epigenetic modulation on hair follicle regeneration, we generated mice with a K14-Cre-mediated loss of DNA methyltransferase 1 (DNMT1). The mutant shows an uneven epidermal thickness and alterations in hair follicle size. When formed, hair follicle architecture and differentiation appear normal. Hair subtypes exist but hair fibers are shorter and thinner. Hair numbers ap...

To examine the roles of epigenetic modulation on hair follicle regeneration, we generated mice with a K14-Cremediated loss of DNA methyltransferase 1 (DNMT1). The mutant shows an uneven epidermal thickness and alterations in hair follicle size. When formed, hair follicle architecture and differentiation appear normal. Hair subtypes exist but hair fibers are shorter and thinner. Hair numbers app...

Calcifying fibrous tumors (CFT) are rare benign tumors. They usually affect children and young adults and the incidence is equal in males and females. The usual clinical presentation is that of a painless mass. A computed tomography scan typically reveals a well-demarcated calcified lesion. CFT usually presents as a solitary mass and the commonest sites of occurrence are in soft tissues, the pl...

A pyogenic granuloma is a reactive hyperplastic inflammatory lesion that arises as result of various stimuli such low-grade local irritation, trauma, hormones, and certain medications. In the oral cavity, it relatively common gingival soft tissue lesion, which originates an expansile growth mucous membrane. It could exhibit aggressive behaviour mimicking malignant lesions with different present...