The assessment of anaesthetic and clinical indices of multimodal therapy of propofol, xylazine, and ketamine was done in West African Dwarf (WAD) goat. Sixteen healthy male WAD goats were assigned into four treatment groups, namely, control (group A) (ketamine 5 mg/kg + xylazine 0.05 mg/kg), group B (propofol 5 mg/kg + xylazine 0.05 mg/kg), group C (propofol 5 mg/kg + ketamine 5 mg/kg), and gro...

BACKGROUND AND PURPOSE We sought to find predictors for hemorrhagic complications in patients with acute ischemic stroke treated with multimodal endovascular therapy. MATERIALS AND METHODS We retrospectively reviewed patients with acute ischemic stroke treated with multimodal endovascular therapy from May 1999 to March 2006. We reviewed clinical and angiographic data, admission CT Alberta Str...

Background: A comprehensive approach to pain management often requires multimodal therapy and a combination of medications. Oncology patients may be prescribed methadone duloxetine as single agents or in for cancer-related pain, particularly neuropathic pain. Duloxetine is also depression anxiety with cancer.

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Surgery offers the only hope for cure. However, the potentially curable method is only possible for a small proportion of those afflicted, for the rest, palliative treatment is indicated. Despite all the treatment options when used as monotherapy, patients with HCC have a poor long term prognosis. In this setting, mult...

Although gender differences in pain and analgesia are well known, it still remains unclear whether men and women vary in response to multimodal pain treatment. This study was conducted to investigate whether men and women exhibited different outcomes after an intensive multimodal pain treatment program. The daily outpatient program consisted of individual treatment as well as group therapy, wit...

BACKGROUND Radical esophagectomy with lymphadenectomy remains the only curative therapy for patients with resectable esophageal squamous cell cancer (ESCC), however, combined treatment modalities may improve survival. Based upon more than 1300 consecutive esophageal resections, we present our current multidisciplinary ESCC approach with analysis in the context of recently published RCTs. METH...

•Brain metastasis from UPSC is rare, with 9 cases in the literature.•UPSC may resemble other endometrial cancers in regard to brain metastatic behavior.•When appropriate, it seems that multimodal therapy offers the best outcomes.

The management of osteoarthritis (OA) in most species consists of a multimodal approach. In small animals, this involves surgically treating the primary cause if possible, reducing the patient’s weight, adapted activity combined with physical therapy, therapeutic nutrition and finally, pharmacological therapy. As previously mentioned, in recent years innovative therapeutic modalities have emerg...

BACKGROUND AND OBJECTIVES The costs and treatment patterns of attention deficit hyperactivity disorder (ADHD) are subjects of health services research in Germany and worldwide. Previous publications focused mainly on prevalent patients and thus research gaps were identified regarding costs and treatment patterns of incident patients before and after the first diagnosis. METHODS Analyses were ...