extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

background: acinetobacter baumannii is gram- negative opportunistic coccobacilli, the most important agent in nosocomial infections with high mortality rate. multidrug resistance in strains isolated from nosocomial infections , making it difficult to treat and sometimes impossible. the aim of the present study was to investigate antibiotic resistance in a. baumannii isolates from iranian patien...

background and objectives: klebsiella species are of the most common bacteria involved in nosocomial and urinary tract infections. genetic elements such as class 1 integrons have an important role in the resistance development. in this study, the share of class 1 integrons, the genetic characterization of the integron cassettes and pfge profiles of the clinical klebsiella isolates are evaluated...

industrial effluents consist many pollutant and heavy metals. bacteria isolated from industrial west water ground may have potential to tolerate heavy metal. in this study we isolate a citrobacter sp. which can resist heavy metal like cu and pb. slurry from industrial west water ground was collected from 22.0663 n, 88.1041 e. the heavy metal content and other parameters of soil were estimated. ...

conclusions the results showed that enterococci are common contaminants in food. indeed, this study indicates a high prevalence of multidrug-resistant enterococci in food of animal origin in iran. isolating some persisting enterococcal isolates revealed that continuous surveillance of antimicrobial resistance in enterococci from food is essential. materials and methods thirty samples of meat, c...

patients and methods in this cross-sectional study, a total of 250 isolates (134 e. coli and 116 k. pneumoniae) were collected and antimicrobial resistances to ampicillin, amoxicillin-clavulanic acid, amikacin, gentamycin, ceftriaxone, ceftazidime, ciprofloxacin and imipenem were evaluated by disc diffusion method and confirmed by e-test. moreover, risk factors for mdr e. coli and k. pneumoniae...

conclusions pmf-dependent efflux mechanism appears to play an important role in the mdr phenotype of a. baumannii clinical strains. background multidrug-resistant (mdr) strains of acinetobacter baumannii have been increasingly reported as a major cause of nosocomial infections, and have created major therapeutic problems worldwide. objectives the aim of the present study was to evaluate the rol...

background: for the first time we tested an association between the human multidrug resistance gene 1 (mdr1) polymorphisms (snps) and idiopathic pulmonary fibrosis (ipf). several mdr1 polymorphisms are associated with pathologies in which they modify the drug susceptibility and pharmacokinetics. materials and methods: we genotyped three mdr1 polymorphisms of 48 ipf patients and 100 control subj...

Background: Shiga toxin-producing Escherichia coli (STEC) are group of E. coli causing bloody diarrhea. The goal of this survey was to determine the prevalence of multidrug resistant shiga toxin-producing E. coli in cattle meat and its contact surfaces. Methods: Swab samples (n=120) were randomly collected from meat and contact surface of butchery shops in Sharkia province, Egypt. Prevalence o...

The PmrA multidrug transporter protein gene was inactivated in Streptococcus pneumoniae strains CP1000 (wild-type) and EBR (mutant with enhanced active multidrug efflux). While the resistance to fluoroquinolones and ethidium bromide shown by EBR was reduced to the wild-type level, neither the susceptibility to reserpine in the presence of ethidium bromide and selected fluoroquinolones, nor the ...