Amyloid-β (Aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in Alzheimer’s disease pathology.Uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. Aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

background: for its toxicity, benzene exposure is one of the main health concerns for high risk occupations like gasoline station workers. however, there is little knowledge about the effect of benzene metabolites on hematological parameters. objective: to evaluate the correlation between the urinary level of trans, trans-muconic acid (t, t-ma), a benzene metabolite, and some hematological para...

this experiment was conducted to evaluate the effects of caffeine and trans-cinnamaldehyde (tc) on growth performance, hematological parameters, stress hormones, immune response, and some blood parameters of broiler chickens. three hundred fifty 1-d-old broiler chicks were randomly assigned to 7 dietary treatments (five pens/ treatment of 10 male broilers each) in a completely randomized design...

Interest in cross-disciplinary research knowledge interchange runs high. Review processes at funding agencies, such as the U.S. National Science Foundation, consider plans to disseminate research across disciplinary bounds. Publication in the leading multidisciplinary journals, Nature and Science, may signify the epitome of successful interdisciplinary integration of research knowledge and cros...

Hemifacial microsomia is a rare congenital malformation of craniofacial structures. Its characteristic features are unilateral underdevelopment of the face and ear malformations. This study describes clinical and radiographical features of a rare case of a 4-year-old hemifacial microsomia patient with underdevelopment of the left side of the face and preauricular skin tags on the affected side...

the nanoparticles of ti-si mixed oxides (ntso) with rutile structure were prepared by sol-gel method in a mixture of alcohol and water as solvent. the solid product was characterized by xrd, ftir, sem, tem, uv, tga and laser raman spectroscopy. the catalytic activity of ntso (5-10 nm) was investigated in the epoxidation of cis stilbene, trans stilbene, and norbornene by using oxidants such as t...

amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

Background and Aim: Over the past 2 decades, endoscopy has become an integral part of the surgical repertoire for pituitary procedures and over the past several decades, the endoscopic endonasal trans sphenoidal approach (EETA) has gradually become an accepted option for pituitary tumors with intra-,supra-,and para-sellar location and extension, because of its minimal invasiveness and high effi...