OBJECTIVES The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with infective endocarditis. SUBJECTS AND METHODS Twenty-nine patients with infective endocarditis and 29 healthy subjects were studied. Plasma MPV values in patients and control subjects were measured on admission and after 2 weeks of specific treatment of infective ...

BACKGROUND Many studies indicated that mean platelet volume (MPV) and platelet distribution width (PDW) may be valuable in the diagnosis and management of clinical disorders; also, serum butyrylcholinesterase activity (BChE) was suggested to be linked to systemic inflammation and oxidative stress. Limited studies measured these readily available markers in children with diabetic ketoacidosis (D...

INTRODUCTION Diabetes mellitus (DM) is a metabolic disorder associated with both microvascular and macrovascular complications. Mean platelet volume (MPV) is a marker of platelet activity, which plays a major role in the development of vascular complications of DM. The aim of this study is to compare the MPV levels before and after the decrease of glycated hemoglobin (HbA1c) levels in a large d...

OBJECTIVE To determine whether mean platelet volume (MPV) is an indicator of disease severity in ocular Behçet's Disease (BD). MATERIALS AND METHODS The study population was 30 newly diagnosed ocular BD patients who presented with active uveitis. These patients had no past history of smoking, drug use, or systemic diseases including diabetes mellitus, hypertension, cardiovascular disease, and...

BACKGROUND Interventricular hemorrhage (IVH) and Broncho pulmonary dysplasia(BPD) commonly occur in premature infants and they associate with platelet dysfunction. The aim of this study was to investigate the association of MPV and occurrence of IVH and BPD. MATERIALS AND METHODS In this cross sectional study, 3 groups including IVH, BPD and control were compared. All participants were preter...

BACKGROUND Currently, the studies on the relationship between type 2 diabetes and platelets indicators were carried out on a selective small sample population generally. Large sample studies in this area are rare, especially in Chinese population. In this study, we aimed to investigate the relationship between type 2 diabetes and the mean platelet volume (MPV), platelet count (PLT) and platelet...

OBJECTIVES To determine the role of hemogram parameters such as platelet count (PLT), mean platelet volume (MPV), and the MPV/PLT ratio in predicting the risk of postoperative vomiting (POV) in children after tooth extraction under deep sedation. METHODS A total of 100 American Society of Anesthesiology Classification I and II pediatric patients who underwent tooth extraction procedures under...

BACKGROUND Increased mean platelet volume (MPV) may reflect increased platelet activation or increased numbers of large, hyperaggregable platelets, and is accepted as an independent coronary risk factor. The adrenergic system has effects on platelet activation and thrombocytopoiesis. OBJECTIVE To assess the effects of autonomic nervous system activity on MPV in patients with acute myocardial ...

The association of increased mean platelet volume (MPV) with myocardial infarction was recognized decades ago (1). Besides acute coronary syndromes, MPV is also associated with increased risk of venous thromboembolism (2), and in patients with a known history of cerebrovascular disease, it is associated with increased risk of stroke (3). MPV is increased in patients with heart failure (4) or di...

BACKGROUND Elevated mean platelet volume may reflect presence of active large platelets, which lead to fatal or non-fatal cardiovascular events. In recent studies, lack of nocturnal blood pressure fall was presented as an independent predictor of poor prognosis in essential hypertension. The relation of raised MPV with left ventricular hypertrophy has also been reported in hypertension. The aim...