Burning mouth syndrome (BMS) is defined as a chronic pain condition characterized by a burning sensation in clinically healthy oral mucosa. Incidence BMS diagnosed in the Department of Oral Medicine - Oral Pathology Dental Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy Bucharest is 16,23%. The etiology of BMS remains far less known. This article makes an overview of the...

The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and cheek to treat local and systemic conditions. The buccal route provides one of the potential route for typically large, hydrophilic and unstable proteins, oligonucleotides and polysaccharides, as well as conventional small drug molecules. The oral cavity has been used a...

The neurofibroma (NF) is a benign tumor of the peripheral nerve sheath that rarely affects the head and neck. However, among neural lesions, this is the one that most frequently affects this region. The NF can be intra or extra-osseous, alone or multiple (associated with type I neurofibromatosis). The most common extra-osseous mouth NF locations are tongue, oral mucosa and lips. In the literatu...

Gongylonema spp. are cosmopolitan spirurid nematodes that are common parasites of wild and domesticated mammals and birds. Gongylonema pulchrum Molin, 1857 is most common in ruminants, where it invades mucosa and submucosa of the mouth, tongue, oesophagus and forestomachs. It extremely rarely occurs in man, and fewer than 60 cases have been reported worldwide. We report a case from the Alsace r...

Tuberculosis of the oral cavity is a very rare disease and accounts for less than one percent of all cases of tuberculosis. Primary lesions are extremely rare. Presentation is as a single ulcer, may be painful, however multiple painless ulcers have been described. Tongue is the most common oral site involved. The palate, buccal mucosa, floor of the mouth, gingiva, and lips are other possible si...

The Mucocele are benign mucous containing cystic lesion of salivary gland mainly of traumatic origin. The wall of this cavity is formed by compressed bundles of collagen fibrils and it is filled with mucin. Mucoceles are known to occur most commonly on the lower lip, followed by the floor of mouth and buccal mucosa being the next most frequent sites. This paper presents oral mucosal lesion on l...

Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa in the absence of mucosal abnormality. Various local, systemic and psychological factors are associated with BMS, but its aetiology is not fully understood. Recently, significant inroads have been made, producing a better understanding of this complex condition. The aim of the current paper is to explore the...

Squamous cell carcinoma and its histologic variants account for over 90% of all malignancies of the oral cavity. Early squamous cell carcinoma often presents as a white lesion (leukoplakia), red lesion (erythroplakia), or a combination of both (erythroleukoplakia). 1,2,3,4 However, with time, superficial ulceration of the mucosal surface may develop. As the lesion grows, it may become an exophy...

Cowden's syndrome (CS) is a rare genodermatosis, of autosomal dominant inheritance and variable phenotype, principally characterized by the formation of hamartomas in various organs, including skin, thyroid, breast, brain, and gastrointestinal tract and by the increased risk for the development of malignancy. The present report details the features of a very rare presentation of Cowden's syndro...

fails to respond to the action of carcinogenic hy drocarbons when administered from within the lumen (see reviews 1, 6, 7, 12). Such carcinogens are known to induce tumors of glandular mucosa when injected into the submucosa (4, 5, 11) but induce only tumors of the squamous epithelium of the forestomach when administered by mouth (2, 8, 10). On the assumption that the "mucus barrier" (6) might ...