BACKGROUND In vivo reflectance confocal microscopy (RCM) is a promising non-invasive skin imaging technique that could facilitate early diagnosis of basal cell carcinoma (BCC) instead of routine punch biopsies. However, the clinical value and utility of RCM vs. a punch biopsy in diagnosing and subtyping BCC is unknown. OBJECTIVE To assess diagnostic accuracy of RCM vs. punch biopsy for diagno...

A nosocomial polyclonal outbreak associated to bacteremia caused by different Burkholderia cepacia complex (BCC) species and clones is reported. Molecular characterization identified Burkholderia stabilis, Burkholderia contaminans, and Burkholderia ambifaria among BCC isolates obtained from patients in neonatal and adult intensive care units. BCC was also isolated from an intrinsically contamin...

International guidelines on the diagnosis and treatment of basal cell carcinoma (BCC) recommend a punch biopsy in the majority of clinically suspected BCC prior to treat ment. This is to confirm diagnosis and to identify the histological subtype (superficial, nodular, aggressive), which is necessary to know for optimal treatment selection (1, 2). A punch biopsy can detect the most aggressive su...

this research identifies returns to scale (rts) of efficient decision making units (dmus) with desirable (good) and undesirable (bad) inputs and outputs by presenting a new dea (data envelopment analysis) approach. in this study, we first introduce a new input-output oriented model to determine efficient dmus in the presence of undesirable factors and then, returns to scale of these dmus are es...

PURPOSE Nonmelanoma skin cancer is the most common cancer and comprises basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The incidence of SCC increases drastically in immunosuppressed individuals, suggesting a critical role of the immune system in controlling SCC. To find an explanation for the selective immunosurveillance of SCC, we investigated the expression of cancer-testis (CT...

In this paper odd-order B-spline filters are proposed to reconstruct volumetric data sampled on an optimal Body-Centered Cubic (BCC) grid. To make these filters nearly interpolating, we adapt a previously published framework, which is based on a discrete frequency-domain prefiltering. It is shown that a BCC-sampled B-spline kernel is not invertible, therefore the interpolation constraint cannot...

Nonmelanoma skin cancers (NMSCs), which include basal and squamous cell cancers are the most common human cancers. BCCs have a relatively low metastatic rate and slow growth and are frequently underreported. Whilst there is a definite role of sunexposure in the pathogenesis of BCC, several additional complex genotypic, phenotypic and environmental factors are contributory. The high prevalence a...

Introduction Basal cell carcinoma (BCC) is the most commonly occurring cancer worldwide, and the overall incidence is still rising. Unfortunately, the cancer registry in Poland does not record BCC individually. Thus, the incidence of BCC in a defined population is unknown. Aim Analysis of incidence rates of primary BCC in central Poland during 16 years considering sex, site distribution and a...

basal cell carcinoma (bcc) is the most common cancer among humans, and the standard treatment is surgery. other modalities are reserved as a second line of treatment. topical chemotherapy may be used in primary bcc. systemic chemotherapy has no role in the primary treatment of bcc, although it may be efficacious in metastatic cases. we report the case of a patient with persistent recurrent bcc ...