An elderly patient with chronic myelomonocytic leukaemia developed severe bone pains and acute gonarthritis. Intravenously administered cytosine arabinoside brought dramatic relief of the bone pains and led to a rapid subsidence of the arthritis, without achieving haematological remission.

Background There is increasing evidence suggesting that the Locus Coeruleus plays a role in pain-related anxiety. Indeed, we previously found that prolonged arthritis produces anxiety-like behavior in rats, along with enhanced expression of phosphorylated extracellular signal-regulated kinase 1/2 (a marker of plasticity) in the Locus Coeruleus. However, it is unknown how this effect correlates ...

A minority of osteoid osteomas are found to be juxta-articular and within the small bones of the wrist. We present a 30-year-old man diagnosed with an osteoid osteoma of the lunate bone, presenting with 3 years of left wrist pain, swelling and reduced range of motion. Given the patient's background and laboratory testing, consideration was given to both inflammatory and infectious causes and th...

BACKGROUND Skeletal complication of brucellosis is common in endemic region of brucellosis, but its frequency has not been clearly determined. The aim of this study was to determine the frequency of skeletal complication in brucellosis patients in Babol, north of Iran. METHODS From 2005-2015, 1252 cases of brucellosis were diagnosed at the Department of Infectious Diseases, Ayatollah Rouhani ...

Osteoarthritis is the most frequent form of arthritis and the main cause of chronic disability [1]. The disease increases with longevity and obesity [2-4]. Gonarthritis is among the most prevalent and disabling types of OA [5]. The bilateral knee OA is more frequent than unilateral affecting 5% versus 2%, respectively of those between 45 and 74 years [6]. Of 63 patients followed for 11 years, 1...

Introduction Acute unexplained monarthritis from which purulent-appearing but sterile synovial fluid is obtained has been dubbed pseudoseptic arthritis (1). A number of entities have been described that can present in this manner. Empirical therapy for septic arthritis is still indicated in these presentations, but can be discontinued when an alternative explanation for the acute condition is i...