Rhodium(iii)-catalyzed C-H olefination of aryl phosphonic esters is reported for the first time. In this mild and efficient process, the phosphonic ester group is utilized successfully as a new directing group. In addition, mono-olefination for aryl phosphonates is observed using a phosphonic diamide directing group.

Frequent observations have been made of the increased rate of hydrolysis of relatively labile phosphate compounds in acid molybdate solution (e.g. phosphocreatine (I), acetyl phosphate (2), and 1,3-diphosphoglyceric acid (3)). A study by Weil-Malherbc and Green (4) indicated that ATP, pyrophosphate, phosphoenolpyruvate, and fructosr B-phosphate were hydrolyzed appreciably in the pH range 3 to 5...

Two years ago, a modification (1) of the Bell-Doisy phosphate method was published and at that time technique ‘was given for its application to inorganic phosphorus in blood and urine. Since then its use has been extended to a variety of analytical procedures, some of which are given below. In principle the method consists of the formation of phosphomolybdic acid and its subsequent reduction by...

Frequent observations have been made of the increased rate of hydrolysis of relatively labile phosphate compounds in acid molybdate solution (e.g. phosphocreatine (I), acetyl phosphate (2), and 1,3-diphosphoglyceric acid (3)). A study by Weil-Malherbc and Green (4) indicated that ATP, pyrophosphate, phosphoenolpyruvate, and fructosr B-phosphate were hydrolyzed appreciably in the pH range 3 to 5...

A novel tungstate and molybdate binding protein has been discovered from the hyperthermophilic archaeon Pyrococcus furiosus. This tungstate transport protein A (WtpA) is part of a new ABC transporter system selective for tungstate and molybdate. WtpA has very low sequence similarity with the earlier-characterized transport proteins ModA for molybdate and TupA for tungstate. Its structural gene ...

We have recently purified the modulator of the glucocorticoid-receptor complex from rat liver. Purified modulator inhibits glucocorticoid-receptor complex activation and stabilizes the steroid-binding ability of the unoccupied glucocorticoid receptor. Since these activities are shared by exogenous sodium molybdate, modulator appears to be the endogenous factor that sodium molybdate mimics. In t...