M etolachlor and excess Mn:+ (acid soil stress) induce alterations in gibberellin precursor biosynthesis that can explain the morphological responses to these physiological stresses. Oxa­ betrinil protects sorghum [Sorghum bicolor (L.) Moench] from the influence o f metolachlor and excess Mn2+. Sorghum cultivar variations in response to excess M n2+ are explicable as dif­ ferential rates o f tv...

Recently, an MRI-detectable, neuronal tract-tracing method in living animals was introduced that exploits the anterograde transport of manganese (Mn2+). We present the results of experiments simultaneously tracing manganese chloride and wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) to evaluate the specificity of the former by tracing the neuronal connections of the basal ...

Sheep liver cytoplasmic aldehyde dehydrogenase is strongly inhibited by Mg2+, Ca2+ and Mn2+. The inhibition is only partial, however, with 8-15% of activity remaining at high concentrations of these agents. In 50 mM-Tris/Hcl, pH 7.5, the concentrations giving half-maximal effect were: Mg2+, 6.5 micrometers; Ca2+, 15.2 micrometers; Mn2+, 1.5 micrometer. The esterase activity of the enzyme is not...

Applicability of phototherapeutic CO-releasing molecules (photoCORMs) is limited because they are activated by harmful and poorly tissue-penetrating near-ultraviolet light. Here, a strategy is demonstrated to activate classical photoCORM Mn2(CO)10 using red light (635 nm). By mixing in solution a triplet photosensitizer (PS) with the photoCORM and shining red light, energy transfer occurs from ...

The yeast Ca2+ adenosine triphosphatase Pmr1, located in medial-Golgi, has been implicated in intracellular transport of Ca2+ and Mn2+ ions. We show here that addition of Mn2+ greatly alleviates defects of pmr1 mutants in N-linked and O-linked protein glycosylation. In contrast, accurate sorting of carboxypeptidase Y (CpY) to the vacuole requires a sufficient supply of intralumenal Ca2+. Most r...

Naturally occurring metallothionein (MT) is a metal binding protein, which binds to seven Zn2+ through 20 conserved cysteines and forms two metal binding clusters with a Zinc-Blende structure. We demonstrate that the MT, when substituting the Zn2+ ions by Mn2+ and Cd2+, exhibits magnetic hysteresis loop observable by SQUID from 10 to 330 K. The magnetic moment may have originated from the bridg...

Background Stem cell therapy in the heart is limited by an inability to track transplanted cell survival. To address this limitation, we used human amnion-derived mesenchymal stem cells (hAMSCs), which exhibit longer in vivo survival, and Manganese (Mn2+)-Enhanced MRI (MEMRI), which enters live stem cells to augment T1 signal. We tested Mn2+ pre-labeling of hAMSCs in vitro and whether MEMRI wou...

A dominant feature of the inorganic chemistry of manganese is the variety of complexes that can be made with different oxidation levels ( + 11+ IV) of the manganese, and living systems have utilized this property in that manganese-containing en­ zymes are involved in many diverse redox func­ tions [1]. The biological function that has generat­ ed most interest is the photosynthetic oxygen evolv...

Natural estrogens, such as 17beta-estradiol (E2), are the main substances responsible for estrogenic activity found in domestic sewage. In the work described herein, the degradation of E2 has been investigated by single ozonation and catalytic ozonation in the presence of manganese ion (Mn2+) and oxalic acid. The presence of Mn2+ and oxalic acid in the ozonation processes significantly improved...