Mitochondria play important roles in energy generation and homeostasis maintenance eukaryotic cells. The damaged or superfluous mitochondria can be nonselectively selectively removed through the autophagy/lysosome pathway, which was referred as mitophagy. According to molecular machinery for degrading mitochondria, occur macromitophagy micromitophagy. In this study, we show that endosomal sorti...

Astaxanthin (AX) is a carotenoid that exerts potent antioxidant activity and acts in the lipid bilayer. This study aimed to investigate effects of AX on muscle-atrophy-mediated disturbance mitochondria, which have Tail suspension was used establish muscle-atrophied mouse model. diet fed tail-suspension mice prevented loss muscle weight, inhibited decrease myofiber size, restrained increase hydr...

This study has demonstrated that in the ameba, Pelomyxa carolinensis Wilson (Chaos chaos L.) the limiting membranes of mitochondria and postdivision nuclei are often continuous. The morphological relationship may be functional in that it permits an exchange of material resulting directly or indirectly in an increased enzyme content of the mitochondria. It is suggested that through a series of p...

The release of tributylphosphine in mitochondria induces morphological changes and upregulates specific genes from the integrated stress response, such as CHAC1.