Abstract Concept of patient prosthesis mismatch came into existence from 1978 onward when Rahimtoola first defined it as “mismatch can be considered to present the effective prosthetic valve area, after insertion patient, is less than that a normal human valve.” Patient produces higher expected pressure gradient through normally functioning valve. Since ball caged mechanical in descending aorta...

A patient underwent exercise testing during evaluation for unexplained dyspnea. Evidence of ventilation-perfusion mismatch was noted and subsequent testing revealed multiple pulmonary emboli. Ventilation perfusion parameters by serial exercise testing progressively improved during the course of the patient's illness but did not totally normalize. A discussion of the utility of exercise testing ...

Microsatellite instability (MSI) is the molecular hallmark of DNA mismatch repair deficiency. Since its initial description in colorectal cancer (CRC) in 1993 and its association with Lynch syndrome, the most common inherited cancer predisposition world-wide, accumulating evidence suggests that MSI status may also be of concrete prognostic and predictive value in the management of sporadic CRC....

The strain induced by lattice mismatch at the interface is responsible for the different value of the band discontinuities observed recently for the AlN/GaN (AlN on GaN) and the GaN/AlN (GaN on AlN) polar (0001) interface. We present a first-principles calculation of valence band offsets, interface dipoles, strain-induced piezoelectric fields, relaxed geometric structure, and formation energies...

This review is focused on the general aspects of the DNA mismatch repair (MMR) process. The key proteins of the DNA mismatch repair system are MutS and MutL. To date, their main structural and functional characteristics have been thoroughly studied. However, different opinions exist about the initial stages of the mismatch repair process with the participation of these proteins. This review aim...

Cracks free mullite-alumina Functionally Gradient Ceramics (FGC) have been obtained by sequential slip casting of Mullite-alumina slurries with diserent mullite/alumina ratios. These slurries were prepared with 65 % solids content and viscosities rangingpom 10 to 40 mPa.s. 7he presence of cracks perpendicular to the FGC layers have been attributed to residual stresses developed because of the m...

We analyze the properties and stability of two-color discrete localized modes in arrays of channel waveguides where tunable quadratic nonlinearity is introduced as a nonlinear defect by periodic poling of a single waveguide in the array. We show that, depending on the value of the phase mismatch and the input power, such two-color defect modes can be realized in three different localized states...