To integrate photothermal therapy (PTT) with chemotherapy for improving anticancer efficiency, we developed a novel and multifunctional doxorubicin (DOX) conjugated copper sulfide nanoparticle (CuS-DOX NP) drug delivery system using hydrazone bonds to conjugate carboxyl-functionalized copper sulfide nanoparticles (CuS NPs) and DOX. On the other hand, the hydrazone bonds could be used for improv...

Photothermal cancer therapy has attracted considerable interest for cancer treatment in recent years, but the effective photothermal agents remain to be explored before this strategy can be applied clinically. In this study, we therefore develop flower-like molybdenum disulfide (MoS2) nanoflakes and investigate their potential for photothermal ablation of cancer cells. MoS2 nanoflakes are synth...

OBJECTIVES To assess the burden of malaria on health services, describe the clinical presentation of severe malaria in children, and identify factors associated with mortality by means of a prospective observational study. SETTING Two public hospitals in Taiz (mountain hinterland) and Hodeidah (coastal plain), Yemen. PARTICIPANTS Children aged 6 months to 10 years. RESULTS Of 12,301 paedi...

OBJECTIVE Photobiostimulation and photobiomodulation (PBM) are terms applied to the manipulation of cellular behavior using low intensity light sources, which works on the principle of inducing a biological response through energy transfer. The aim of this investigation was to identify a laboratory assay to test the effect of an infrared diode laser light (808 nm) on cell fission rate. MATERI...

THE AIM OF THE STUDY WAS TO ASSESS THE EFFICACY OF LASER THERAPY (AT DIFFERENT WAVELENGTHS: 940, 808, and 658 nm) for treating pressure ulcers. The primary endpoint in this trial included both the percentage reduction of the ulcer surface area and the percentage of completely healed wounds after one month of therapy (ulcer healing rate). The secondary endpoint was the ulcer healing rate at the ...

CONTENTS INTRODUCTION ............................................................................................................ 806 THE MULTIPLE BIOLOGICAL FUNCTIONS F tRNA ................................................ 807 tRNA Cycle in Protein Synthesis .............................................................................. 807 tRNA and the Regulation of Enzyme Synthesis ............

Photothermal therapy has attracted significant attention as a minimally invasive therapy methodology. In this work, we report PEGylated nickel carbide nanocrystals (Ni3C NCs) as an efficient photothermal agent for the first time. The nanoparticles exhibit a broad absorption from the visible to the near-infrared regions and a rapid rise in temperature when irradiated by an 808 nm laser even at a...

Oculocutaneous albinism (OCA) is an autosomal recessive disorder characterized by hypopigmentation of the skin, hair, and eyes accompanied with ophthalmologic abnormalities. Molecular genetic test can confirm the diagnosis of the four subtypes of OCA (OCA1-4). Herein, we report a Chinese family with two patients affected by OCA. Mutations of TYR, OCA2, TYRP1, and SLC45A2 were examined by using ...

The mortality response of lightbrown apple moth, Epiphyas postvittana (Walker), to a controlled atmosphere (CA) cold storage treatment for apricots was investigated. The mean estimated times for 99% mortality (LT99) of 1st and 5th instar larvae inoculated onto apricots and exposed to 1.5% O2, 3% CO2 (CA) at 0°C, were 19.9 ± 0.13 and 22.4 ± 0.24 d, respectively. The treatment time for 50% mortal...

Identifying the main byproducts of SF6 decomposition proves to be an effective strategy for determining nature and severity internal discharge faults in gas-insulated switchgears (GISs). In this research, it was suggested utilize coordination polymer Zr-MOF-808 as a sensor decomposition. This study examined adsorption its products (CF4, CS2, SO2, SO2F2, SOF2) on Zr-MOF-808, utilizing Gaussian16...