نتایج جستجو برای: mirna and multiple sclerosis
تعداد نتایج: 16931715 فیلتر نتایج به سال:
Introduction: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). It is an Auto immune disease whose cause is still unknown though some factors can be named as its cause such as genetics, geographic element and viral agents. HSV is among the infection agents that may be involved in pathogenesis of MS. The aim of this study was to use a new technique called lo...
multiple sclerosis (ms) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. the main pathogenesis of ms has long been thought to be an immune mediated disorder of the central nervous system. the function of the immune system is under the influence of vitamin d which as a modulator of immune response could play a...
Introduction: There is a relationship between stress and the onset of Multiple Sclerosis (MS). So, controlling stress is necessary in patients with MS. We aimed to investigate the effect of educational intervention base on BASNEF model to promote behaviors in patients with multiple sclerosis in stress management. Methods: This is a quazi-experimental intervention study. This study was perfo...
Introduction: Multiple sclerosis is a chronic, progressive and degenerative myelin sheath disease of the central nervous system. It frequently occurs in young people in the productive stage of life who are solicitous about their role and family responsibilities. One of the treatment and vigilance intervention index in improvement of chronic illness is quality of life. The objective of the imple...
vitamin d has long been speculated to reduce the risk of multiple sclerosis (ms). however, its role in development and modulating the course of ms has yet to be clarified. to date, there is no scientific evidence for the use of vitamin d as monotherapy for ms in clinical practice and perplexities still exist on potential disadvantages of vitamin d intake. we hypothesize that vitamin d may be ef...
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background: little in known regarding the clinical relevance of sirt1 in multiple sclerosis (ms). here, we aimed to evaluate mrna expression, protein level and enzyme activity of sirt1 in peripheral blood mononuclear cells (pbmcs) isolated from relapsing –remitting ms patients (rrms) and healthy controls. materials and methods: twenty patients with rr-ms and twenty two age- and sex-matched he...
background: neurobrucellosis is a rare complication of brucellosis. acute meningitis and encephalitis are the most common clinical manifestations; however, symptoms of these two conditions may be subacute and diagnosis requires a high index of suspicion in patients from endemic areas. diagnosis is often based on neurological symptoms, serology, and suggestive brain imaging because cerebrospinal...
background: there has been a global rising trend in recent years in the incidence of multiple sclerosis (ms). despite being an ms low-risk region, this disease has also been recently on the rise in the middle east. as part of the middle east, iran has not been spared either; however, the cause of this dramatic increase remains to be discovered. the present study reviews possible reasons for thi...
conclusions the orem-based self-care model program can be a useful tool to improve sleep quality of patients with ms. future studies can be directed to investigate the effects of such interventions on other common problems of patients. results before the intervention, there was no significant difference between the two groups with regard to mean scores of sleep quality (p = 0.22). both groups r...
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