background: it has been reported that curcumin has anti inflammatory, antibacterial, anti tumor and analgesic properties. objective: the purpose of this study was to investigate the efficacy of curcumin in the treatment of minor aphthous stomatitis. methods: the study was a two week, randomized, double blind, placebo controlled of patients with minor aphthous. patients between 18 and 65 years o...

Bacillus subtilis, like many bacteria, will choose among several response pathways when encountering a stressful environment. Among the processes activated under growth-restricting conditions are sporulation, establishment of motility, and competence development. Recent reports implicate ComK and MecA-ClpC as part of a system that regulates both motility and competence development. MecA, while ...

Staphylococcus aureus pathogenesis is directed by regulatory proteins and RNAs. We report the case of an RNA attenuating virulence and host uptake, possibly to sustain commensalism. A S. aureus sRNA, SprC (srn_3610), reduced virulence and bacterial loads in a mouse infection model. S. aureus deleted for sprC became more virulent and increased bacterial dissemination in colonized animals. Conver...