objective: nowadays notable increase in acquired resistance of candida species to antifungal drugs and necessity of using agents with antifungal properties is unavoidable. in some plants due to presence of components such as polyphenols have antimicrobial properties. in this study antifungal effects of essential oils of thymus vulgaris, petroselinum crispum, cuminum cyminum and bunium persicum ...

The objective of this study is to evaluate whether the accumulation model developed by Zarfl et al. (2008) could be used to predict the minimal inhibitory concentration (MIC) of a group of antibacterial fluoroquinolones (FQs) for Escherichia coli (E. coli). Our model, which is based on the "Fick-Nernst-Planck" equation and the permeability of the neutral and charged species as well as the physi...

Essential oils from different organs of Ageratum fastigiatum (Gardn.) R. M. King et H. Rob., obtained by hydrodistillation were analyzed through Gas Chromatography and Gas Chromatography/Mass Spectrometry. The essential oils were tested for antimicrobial activity by the agar-diffusion method and minimal inhibitory concentration (MIC). The main compounds found were β-caryophyllene, germacrene D ...

Daily use of mouthwash is generally recommended to control dental plaque development and limit further adhesion oral bacteria. To this purpose, Chlorhexidine di-gluconate (CHG)-containing products are still the most used antiseptic in health. The aim study was compare antimicrobial antibiofilm activity three different commercial formulations containing CHG at same concentration (0.2%) on main e...

Methicillin resistant Staphylococcus aureus (MRSA) is increasingly being described as a cause of acute sinusitis. We present a patient with acute MRSA sinusitis complicated by rapid intracranial extension, marginal vancomycin susceptibility (MIC = 2 mg/L), delayed drainage of intracranial abscess, and subsequent development of rifampin resistance. Given the relatively high risk of intracranial ...

The in vitro activity of lysostaphin against clinical isolates of Staphylococcus aureus was determined by conventional tube-dilution methods. For comparison, minimal inhibitory concentration (MIC) values were also determined for penicillin G, ampicillin, methicillin, ristocetin, vancomycin, and erythromycin. Phage type and penicillinase and coagulase production were determined for each isolate....

The present work reports the study of the antimicrobial activity of four quinoxaline N,N-dioxide: quinoxaline 1,4-dioxide, 2-methylquinoxaline 1,4-dioxide, 6chloro-2,3-dimethylquinoxaline 1,4-dioxide and 3-benzoyl-2-methylquinoxaline 1,4dioxide against Geobacillus stearothermophilus ATCC 10149, Escherichia coli ATCC 25922, Escherichia coli HB101, Escherichia coli (blaTEM, blaCTX-M) and Salmonel...

From the methanol extract of the stem bark of Ficus exasperata, a new sphingolipid named Ficusamide, (2S,3S,4R,11E)-2-[(2',3'-dihydroxyhexacosanoylamino)]-11-octadecene-1,3,4-triol (1), along with three known furanocoumarins, (S)-(-) oxypeucedanin hydrate (2), (R)-(+) oxypeucedanin hydrate (3), bergapten (5-methoxypsoralen) and six other known compounds, were isolated. Their structures were cha...

Background: Klebsiella pneumoniae is one of the most important bacteria that cause nosocomial infections. This opportunistic pathogen has a high potential for antibiotic resistance and can generate a thick layer of biofilm. Nowadays, antibiotic resistant strains are emerging and widely spreading worldwide. Thus, it is necessary to combat drug-resistant strains through the use of novel drugs (su...