نتایج جستجو برای: mimotope

تعداد نتایج: 237  

Journal: :Applied and environmental microbiology 1999
Q Yuan J J Pestka B M Hespenheide L A Kuhn J E Linz L P Hart

Monoclonal antibody 6F5 (mAb 6F5), which recognizes the mycotoxin deoxynivalenol (DON) (vomitoxin), was used to select for peptides that mimic the mycotoxin by employing a library of filamentous phages that have random 7-mer peptides on their surfaces. Two phage clones selected from the random peptide phage-displayed library coded for the amino acid sequences SWGPFPF and SWGPLPF. These clones w...

2015
Seth M. Daly

[This corrects the article DOI: 10.1371/journal.pone.0111198.].

2012
Marco Schiavone Giuseppe Fiume Antonella Caivano Annamaria de Laurentiis Cristina Falcone Francesca Fasanella Masci Enrico Iaccino Selena Mimmi Camillo Palmieri Antonio Pisano Marilena Pontoriero Annalisa Rossi Annarita Scialdone Eleonora Vecchio Concetta Andreozzi Maria Trovato Jan Rafay Boris Ferko David Montefiori Angela Lombardi Giulia Morsica Guido Poli Ileana Quinto Vincenzo Pavone Piergiuseppe de Berardinis Giuseppe Scala

The Bridging Sheet domain of HIV-1 gp120 is highly conserved among the HIV-1 strains and allows HIV-1 binding to host cells via the HIV-1 coreceptors. Further, the bridging sheet domain is a major target to neutralize HIV-1 infection. We rationally designed four linear peptide epitopes that mimic the three-dimensional structure of bridging sheet by using molecular modeling. Chemically synthesiz...

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