Food allergy represents a highly up-to-date and continually increasing problem of modern man. Although being present in all ages, it most often occures in children aged up to three years. Sensitization most often occurs by a direct way, but it is also possible to be caused by mother's milk, and even transplacentally. Predisposition of inadequate immune response to antigen stimulation, reaginic ...

BACKGROUND Better understanding of the association between early life lipid intakes and the development of allergic diseases is needed. OBJECTIVE We prospectively studied breast milk content of n-6, n-3, and trans fatty acids in relation to allergic symptoms at the ages of 1 and 4 years. METHODS Fatty acid content was determined in breast milk samples of 265 (158 allergic and 107 nonallergi...

OBJECTIVE To critically examine the published literature to determine whether feeding hydrolyzed infant formulas from birth has a role in allergy prevention. DATA SOURCES We identified data through a MEDLINE search using allergy prevention and infant formulas as indexing terms. The search was restricted to 1985 through the present, English-language articles, and human subjects. STUDY SELECT...

OBJECTIVE Cow's milk allergy has different presentations in children and can cause functional bowel symptoms such as chronic constipation. The aims of this study were to investigate the role of cow's milk allergy as a cause of chronic constipation and effect of cow's milk free diet (CMFD) on its treatment in children. METHODS We performed a randomized clinical study comparing CMFD with cow's ...

UNLABELLED Few studies concerning the importance of food allergy in adolescents and adult patients with atopic eczema exist. The atopy patch tests with food have mostly been studied in infants and children since food allergy plays a role especially in this age group. AIM The evaluation of the contribution of atopy patch tests in the diagnostic work-up of food allergy (to wheat, cow milk, pean...

Sakihara T, Otsuji K, Arakaki Y, Hamada Sugiura S, Ito K. Randomized trial of early infant formula introduction to prevent cow's milk allergy. J Allergy Clin Immunol 2020:S0091-6749(20)31225-2. What is the therapeutic efficacy (CMF) compared with none, in preventing allergy (CMA) among 1-2 month-old babies? Randomized, controlled (RCT). 4 hospitals Okinawa, Japan. Babies, at least 2000g, 35 wee...

Aktaş S, Ergenekon E, Ünal S, Türkyılmaz C, Hirfanoğlu İM, Atalay Y. Different presentations of Cow's milk protein allergy during neonatal period. Turk J Pediatr 2017; 59: 322-328. Cow`s milk protein allergy (CMPA) is the most common cause of allergy occurring in the first year of life due to infant formula or breast-milk of mothers who are drinking cow`s milk or eating cow's milk products. Mos...

BACKGROUND Food allergy can cause life threatening reactions. Currently, patients with severe food allergy are advised to avoid foods which provoke allergic reactions. This has become increasingly difficult as food proteins are being added to a broader range of consumer products. PATIENTS AND METHODS Here we describe our investigations into the allergenicity of a new drink when two cow's milk...

OBJECTIVES The aim of this cross-sectional study was to evaluate whether interleukin 10 (IL10) and transforming growth factor β1 (TGFβ1) gene polymorphisms were associated with persistent IgE-mediated cow's milk allergy in 50 Brazilian children. The diagnostic criteria were anaphylaxis triggered by cow's milk or a positive double-blind, placebo-controlled food challenge. Tolerance was defined a...

BACKGROUND Currently, there is no mandatory labelling of allergens for non-pre-packed foods in the EU. Therefore, consumers with food allergy rely on voluntary information provided by the staff. The aim of this study was to characterize allergic reactions to non-pre-packed foods and to investigate whether staff in bakery shops were able to give advice regarding a safe product choice. METHODS ...