OBJECTIVE Migraine is a disease of high prevalence with important impact on people's daily activities. The study aimed at assessing the distribution of migraine in adult population and some of its determinants. METHODS A cross-sectional population-based study was conducted with a multi-stage and probabilistic sampling. A total of 2,715 individuals aged 20 to 64 years old living in the urban a...

BACKGROUND AND PURPOSE There are few studies that have investigated predictive factors related to migraine prophylaxis of which produced inconsistent results. The aim of this study was to identify factors that can predict the treatment response to topiramate prophylaxis in pediatric patients with migraine. METHODS One hundred and thirteen patients who were older than 7 years and received topi...

Abstract Background Calcitonin gene related peptide (CGRP) is known to be the most potent vasodilator of body, and it promotes migration inflammatory cells. CGRPβ isoform located along enteric nervous system, CGRPα mainly present in central system. key molecule migraine, an entity with digestive symptoms. It has been suggested that migraine prevalence increased bowel disease (IBD). The aim stud...

As I NOTED in another paper, whenever I see a patient with a severe, bizarre, or long-lasting migraine refractory to treatment, I suspect that I am dealing with migraine plus something else -such as a mild psychosis, an unrecognized epilepsy, a cerebral arteriosclerosis, or a constitutional inadequacy. Elsewhere, I have described a series of patients with migraine plus a mild psychosis. Now I p...

how to cite this article: nejad biglari h, karimzadeh p, mohammadi kord-kheyli m, hashemi sm. migraine types and triggering factors in children. iran j  child neurol 2012;6(2):33-38. objective migraine is a common problem in children and the mean prevalence of migraine in europe among 170,000 adults was 14.7% (8% in men and 17.6% in women) and in children and youth (36,000 participants), the pr...

Physiological and emotional stressors are associated with or provoke each migraine attack and cause structural and functional changes in the central nervous system. The hippocampus, a limbic structure important in anxiety-related behavior, is vulnerable to long-term stress. Given that catechol-O-methyltransferase (COMT) is widely distributed in the hippocampus and its genetic variation is thoug...

background : a wide range of preventive medications for migraine attacks, with varying efficacy is currently in use. studies comparing the efficacies of these drugs would be of value in the proper treatment of the disease. the present study compared the frequency, duration and intensity of migraine attacks during and following treatment with cyproheptadine (4 mg, twice daily) or blellergal (bel...

multiple sclerosis (ms) and migraine are two common neurological disorders affecting women more than men. sleep quality impairment has been reported in both diseases. the goal of this study was to compare sleep quality and depression between women with ms and migraine. seventy women with migraine and 75 women with ms were enrolled in this study. participants were asked to fill-out valid and rel...

OBJECTIVES To determine the frequency of hyperintense foci in migraine patients and the relationship with migraine headache characteristics and cardiovascular risk factors. METHODS Ninety patients with migraine headache (70 without aura and 20 with aura) were enrolled and interviewed. Information on their headache (severity, frequency, and mean disease duration) and other related data was obt...

The results of neuroimaging studies on migraines have shown that the functions and functional connectivity networks of some brain regions are altered in migraine patients, and different brain structure volumes have also been observed in recent years. However, it is still not known whether the mean thickness of the cortex is different in migraine patients.A total of 48 migraine without aura (MWo...