The sensitivity of anuran to the effects habitat destruction and contamination has led a preoccupying global decline in their populations. Morphological biomarkers such as micronuclei other erythrocyte nuclear abnormalities (ENAs), well occurrence hepatic melanin, can be used evaluate impacts. In present study, these two parameters were combined for situ assessment soybean cultivation on grassf...

Petroleum refinery wastes contain mixtures of toxic compounds including Polycyclic Aromatic Hydrocarbons (PAH) which may pose genotoxic threats to the biota. The objective present study was assess potential wastewaters petroleum at Sapugaskanda, Sri Lanka using erythrocytic micronuclei and nuclear abnormalities as biomarkers in fish Oreochromis niloticus exposed wastewater under controlled labo...

Objective: Nanotechnology is an emerging technology which has wide applications in many fields. Prime concern of research nanotechnology the synthesis nano-material with controlled size and shape. Recently, biosynthesis metallic nano-particles gained popularity owing to its eco-friendliness. The increasing use Copper nanoparticles (CuNPs) medicine industry demands understanding their potential ...

Micronuclei are small membrane-enclosed cytoplasmic bodies containing whole or fragmented chromosomes, which are formed during anaphase in aberrant mitosis and in response to genotoxic stress. in the latter scenario, the formation of micronuclei can be used to assess the toxicity of various chemicals and drugs. A report by Rello-varona et al. in a previous issue describes the elimination of mic...

Background: This study was conducted to investigate both the genotoxicity effects of M. officinalis aqueous extract on blood cells and the pathologic changes in the renal, cardiac and splenic tissues of Oncorhynchus mykiss. Methods: 300 fish (Oncorhynchus mykiss) were divided randomly into three groups (N=100 each), consisting of group, 1 (control), and groups 2 and 3 (experimental), which rec...

As micronuclei (MN) derive from chromosomal fragments and whole chromosomes lagging behind in anaphase, the MN assay can be used to show both clastogenic and aneugenic effects. The distinction between these phenomena is important, since the exposure studied often induces only one type of MN. This particularly concerns the use of MN as a biomarker of genotoxic exposure and effects, where differe...