The effects of atropine and metoclopramide on the lower oesophageal sphincter pressure (LOSP) were studied in 12 healthy volunteers using oesophageal pressure transducers. Atropine decreased LOSP significantly at 5 min after i.v. injection (P less than 0.005) and this change was sustained for 60 min. Metoclopramide increased LOSP significantly at 3 min after administration i.v. (P less than 0.0...

Presence of heavy metals and antibiotics in the poultry feed even low concentrations is considered as potentially toxic may cause hazardous effects on animal leading to accumulate food chain. This study was performed assess status residue different samples collected from local markets Mymensingh Kishoreganj sadar upazila Bangladesh. A total 40 were analyzed detect concentration three metals- ch...

purpose: to compare the efficacy of granisetron, metoclopramide and dexamethasone in prevention of post operative nausea and vomiting (ponv) after cataract surgery. methods: sixty patients scheduled for cataract surgery with age between 45 to 80 years and with asa class i & ii were enrolled in this clinical trial. the patients were randomly allocated to three 20- person groups. the induction of...

Acute renal papillary necrosis (RPN) in animals is characterized by increased renal lipid accumulation. The excretion of renal lipids into urine has been determined to evaluate their possible use as sensitive early biomarkers for the diagnosis of RPN. This study investigates injury induced by two model nephrotoxins, mefenamic acid (MFA), a non-steroidal anti-inflammatory drug (NSAID), and its a...

Introduction: Oculogyric crisis (OGC) is a dystonic reaction characterized as conjugate and typically upward deviation of the eyes lasting from seconds to hours which seen an uncommon neurologic manifestation. Metoclopramide prokinetic agent that frequently prescribed in treatment nausea, vomiting prophylaxis, vomiting. One side effects after metoclopramide acute reactions.Case Presentation: We...

UNLABELLED The gastroprokinetic agent metoclopramide is known to stimulate catecholamine secretion from pheochromocytomas. The aim of the study was to investigate the mechanism of action of metoclopramide and expression of serotonin type 4 (5-HT(4)) receptors in pheochromocytoma tissues. Tissue explants, obtained from 18 pheochromocytomas including the tumor removed from a 46-year-old female pa...

BACKGROUND & OBJECTIVES Delayed emesis with cisplatin is a significant problem, which is often poorly controlled with conventional antiemetics. There is a relative paucity of data on the control of delayed emesis and rather inconsistent results have been reported. The present study aimed to compare the efficacy and tolerability of ondansetron versus metoclopramide in dose related grades of cisp...

This study was designed to investigate the role of dopaminergic mechanisms in the control of aldosterone secretion in man. Five normal male subjects in metabolic balance at 150 meq sodium/d and 60 meq potassium/d constant intake received the specific dopamine antagonist, metoclopramide, 10 mg i.v. on 2 consecutive d. On the 1st d, the subjects received an infusion of 5% glucose solution (vehicl...