Survival of yeast during starvation has been shown to depend on the nature of the missing nutrient(s). In general, starvation for "natural" nutrients such as sources of carbon, phosphate, nitrogen, or sulfate results in low death rates, whereas starvation for amino acids or other metabolites in auxotrophic mutants results in rapid loss of viability. Here we characterized phenotype, gene express...

BACKGROUND AND PURPOSE Hyperhomocysteinemia is an emerging risk factor for stroke, but little is known about effects of hyperhomocysteinemia on cerebral vascular function. We tested the hypothesis that chronic hyperhomocysteinemia in mice causes endothelial dysfunction in cerebral arterioles through a mechanism that involves superoxide. METHODS Mice heterozygous for a targeted disruption of t...

Drought is one of the main constraints determining forest species growth, survival and productivity, and therefore one of the main limitations for reforestation or afforestation. The aim of this study is to characterize the drought response at the physiological and molecular level of different Pinus halepensis (common name Aleppo pine) seed sources, previously characterized in field trials as d...

Methyl mercaptan production by oral bacteria is thought to be one of the main causes of oral malodor. We examined the ability of periodontopathic Porphyromonas gingivalis to produce methyl mercaptan from L-methionine and found that the invasive strains W83 and W50 produced large amounts of methyl mercaptan. We cloned and sequenced the mgl gene encoding L-methionine-alpha-deamino-gamma-mercaptom...

the effect of3levels of methionine (nrc recommended, 5 percent more than nrc recommended and 10 percent more than nrc recommended) and 2 levels of fat (0 and 5 percent) on some economical traits (performance and carcass) of broilers using a 2x3 factorial experiment with completely randomized design based on two rearing stages, starter (0-3 wk) and grower (4-6 wk) was studied. anova of the effec...

Poultry by-products and rainbow trout (Onchorhynchus mykiss) viscera are abundant and underutilized resources that can be used as a unique protein source to make protein hydrolysates. In this study protein hydrolysate were made from these two different sources with Alcalase 2.4L. The functional properties of Fish viscera protein hydrolysate (FPH) compared to poultry by-products protein hydrolys...

the aim of this study was to evaluate the effects of balancing low protein diets for methionine and lysine on performance of early lactation holstein cows under hot environmental temperature. twenty one multiparous holstein cows in early lactation were allocated to three experimental rations including, 1) high protein ration with 17.5% cp, 2) medium protein ration with 16% cp and 12 g/d rumen p...

The Cover Feature shows a metal nanoparticle modified with the amino acid L-methionine and adsorption of enzyme acetylcholinesterase (AChE) on methionine-capped surface. Methionine-capped Ag Au nanoparticles (NPs) were tested as inhibitors AChE, they showed moderate inhibitory potential toward AChE. NPs are much larger than molecules cannot enter active site gorge, so inhibition occurs by block...

Methylenetetrahydrofolate reductase catalyzes the reduction of methylenetetrahydrofolate to methyltetrahydrofolate, which serves as the methyl donor for the conversion of homocysteine to methionine in the reaction catalyzed by methionine synthase. Recent studies have provided evidence for association of a common polymorphism of methylenetetrahydrofolate reductase with elevated levels of blood h...