Some pH responsive polymeric matrix of Linseed (Linum usitatissimum), L. hydrogel (LSH) was prepared by free radical polymerization using potassium persulfate (KPS) as an initiator, N,N-methylene bisacrylamide (MBA) as a crosslinker, acrylic acid (AA) and methacrylic acid (MAA) as monomers; while ketoprofen was used as a model drug. Different formulations of LSH-co-AA and LSH-co-MAA were formul...

Bacterial vaginosis is a prevalent state of dysbiosis of the vaginal microbiota with wide-ranging impact on human reproductive health. Based on recent insights in community ecology of the vaginal microbiome, we hypothesize that sustained vaginal DL-lactic acid enrichment will enhance the recruitment of lactobacilli, while counteracting bacterial vaginosis-associated bacteria. We therefore aimed...

A single splat is the building block of a thermal spray coating; thus, investigating single splats is essential to understanding thermal spray coatings and their properties. In this study, the morphology of flame sprayed ethylene methacrylic acid (EMAA) splats, deposited at various stand-off distances (SODs) onto glass and mild steel substrates were investigated using a scanning electron micros...

The preparation, characterization, and in vitro release of 5-aminosalicylic acid (5-ASA) from methacrylic acid (MAA)/perlite composites (APC) prepared via a sol-gel route are reported. The free-radical graft polymerization of methacrylic acid (MAA) onto perlite particles was studied experimentally. The grafting procedure consisted of surface activation with 3-(trimethoxysilyl) propyl methacryla...

This article shows that pressure can be a low-intensity route to the synthesis of polymethacrylic acid. The exploration of perdeuterated methacrylic acid at high pressure using neutron diffraction reveals that methacrylic acid exhibits two polymorphic phase transformations at relatively low pressures. The first is observed at 0.39 GPa, where both phases were observed simultaneously and confirm ...

During the dissolution of cocrystal particles, solution-mediated phase transformation (SMPT) can occur either on particle surface (PS-SMPT) or in bulk solution (BP-SMPT). In this study, we compared effect various polymers PS-SMPT and BP-SMPT for first time using carbamazepine saccharine (CBZ-SAC) as a model drug. Polyethylene glycol 6000 (PEG), polyvinylpyrrolidone K-30 (PVP), hydroxypropyl met...

Hydrogels are three-dimensional polymeric networks those swell quickly by imbibing a large amount of water or deswell in response to even miniscule changes in their external environment. The water uptake or swelling may be thousands of times of their initial volume in water. The volume phase transitions as a response to different stimuli make these materials interesting objects of scientific ob...

A range of amphiphilic statistical copolymers is synthesized where the hydrophilic component either methacrylic acid (MAA) or 2-(dimethylamino)ethyl methacrylate (DMAEMA) and hydrophobic comprises methyl, ethyl, butyl, hexyl, 2-ethylhexyl methacrylate, which provide a broad partition coefficients (log P). Small-angle X-ray scattering studies confirm that these self-assemble to form well-defined...