Introduction: This study has investigated the correlation between IL-6 serum levels with distant metastatic breast cancer incidence. Methods: We recruited female patients at Dr. Soetomo General Hospital from March until May 2022. The sample was divided into 2 groups that consist Metastatic Breast Cancer (MBC) and non-MBC. After stage, were measured. design an observational analytic study, compa...

A method for accurate prediction of prognosis in individual patients with prostatic carcinoma does not exist. The limitations of pathological grading systems may result from the failure of standard pathological examination of fixed dead tissue to accurately assess the biological and metastatic behavior of live tumor cells. Many of the sublines of the Dunning R-3327 rat prostatic adenocarcinoma ...

A method for accurate prediction of prognosis in individual patients with prostatic carcinoma does not exist. The limitations of pathological grading systems may result from the failure of standard pathological examination of fixed dead tissue to accurately assess the biological and metastatic behavior of live tumor cells. Many of the sublines of the Dunning R-3327 rat prostatic adenocarcinoma ...

PURPOSE Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare group of tumors with a wide spectrum of clinical behavior. However, there are no known clinically relevant biomarkers to predict metastasis. EXPERIMENTAL DESIGN To investigate differential gene expression signatures of metastatic vs non-metastatic NETs, we studied cell cycle regulatory genes in 19 metastatic and 22 non-m...

pancreatic neuroendocrine tumors (pnet) are uncommon pancreatic neoplasms, accounting for 1-2% of all pancreatic tumors. however, they have a better prognosis and long-term survival compared to exocrine pancreatic cancer. pnets can be divided into functional or non-functional based upon whether or not they excrete active substances relevant to specific clinical syndromes. skeletal muscle metast...

Background: Pericardial effusion (PE) due to secondary metastasis has rarely been reported in dogs. Case description: This case describes clinical signs and further diagnostics regarding metastatic carcinoma of unknown primary origin (CUP) in refractory PE of a dog. Findings/treatment and outcome: A nine-year-old, castrated mal...

BACKGROUND BAP1 and PBRM1 are frequently mutated in primary clear cell renal cell carcinoma (ccRCC) tumors; however, the frequency and clinical relevance of these mutations in metastatic ccRCC tumors is unknown. Additionally, while intra-tumor heterogeneity has been shown to be common in primary ccRCC, little is known regarding heterogeneity in metastatic ccRCC tumors. MATERIALS AND METHODS W...

The most common sites for metastases of colorectal cancer include the liver, lungs, brain, and regional lymph nodes. However, a limited number reported cases describe colon metastasis to thyroid gland. Metastatic adenocarcinoma gland is rare. majority these with are diagnosed years after initial treatment cancer. discovery usually made routine surveillance imaging, often patients have minimal o...

background: this study testing the effectiveness ,toxicity and tolereability of new chemotherapeutic regimen (consist of irinotecan 5-fu and leucovorin) in locally advanced and metastatic gastric cancer. patients and methods: patients with locally advanced gstric cancer (atleast stage 3)or metastatic gastric cancer that no treated previously with chemotherapeutic agents entered onto this study....

background: systematic treatments such as hormone and chemotherapy are selected according to tumor characteristic after major therapeutic approaches such as surgery. this study attempted to analyze and compare the status of estrogen receptor (er) and progesterone receptor (pr) in primary and recurrent sites of breast cancer in patients. methods: we reviewed all medical records of breast cancer ...