Meningioma is the commonest primary intracranial tumor in adults, with majority being benign. Malignant meningioma exceedingly rare and carries a poor prognosis because of its tendency for local recurrence distant metastasis. We present case 53 years old male anaplastic malignant meningioma, which recurred after excision radiotherapy later metastasised to pleura, bones brain. Keywords: Metastat...

ewing's sarcoma is a relatively common malignant bone tumor that typically occurs in long bone diaphyses of adolescents and young adults of 10-30 years old. often times, all ewing's sarcoma of bone have radiographic abnormalities. diagnosis is usually delayed and can be misdiagnosed as osteomyelitis. bone to bone metastasis occurs, but soft tissue retro bulbar metastasis is rare. this...

background metastatic spinal tumors are common and major causes of pathological spinal fractures that result in severe pain, weakness, and progressive neurological deficits. this study aims to evaluate the efficacy of percutaneous vertebroplasty (pvp) in pain-relief in patients with spinal fractures due to metastatic spinal tumors. methods we evaluated 25 documented cases of metastatic spinal t...

exosomes, as a mediator of cell-to-cell transfer of genetic information, act an important role in intercommunication between tumor cells and their niche including fibroblasts, endothelial cells, adipocytes and monocytes. several studies have shown that tumor cells can influence their neighboring cells by releasing exosomes. these exosomes provide signaling cues for stimulation, activation, prol...

abstract purpose: metastatic breast cancer has remained as an incurable disease. the main objectives of treatments include alleviating of symptoms, delaying disease progression and increasing survival without any adverse effect on the quality of life. the main purpose of this study was to investigate the effects of some clinocopathological factors on the survival of patients with metastatic bre...

conclusions: lymphatic metastasis in patients with oral and maxillofacial scc is closely related to the positive expression of vegf, mmp-9 and timp-2. mmp-9 and timp-2 can affect the progression of cancer, which is valuable for studies on oral and maxillofacial scc genes. objectives: to explore the association between expression of vegf, mmp-9 and timp-2 in oral and maxillofacial scc and clinic...

occurrence of cutaneous metastasis of gastrointestinal cancer is uncommon, with a reported frequency of less than 5 percent.they can occur as the first sign of disease recurrence in a treated patient or as a sign of terminal disseminated cancer or rarely as the first manifestation of an occult malignancy. the cases reported here represent three different manifestation of cutaneous metastasis of...