The formation of a borate-bridged dimeric aluminum Schiff-base compound [salen(Bu)Al]2O2BOMe [salen=N,N’-ethylenebis(salicylidenimine) (1) has been reported. Complex 1 crystallizes in a triclinic P space group with a=14.57, b=15.15, c=15.84 Å and a=96.92, b=90.82, g=105.538. The crystal structure shows the presence of a metaborate (MeOBO2 2– ) bridge between two five-coordinate aluminum atoms w...

Salen Mn complexes, including EUK-134, EUK-189 and a newer cyclized analog EUK-207, are synthetic SOD/catalase mimetics that have beneficial effects in many models of oxidative stress. As oxidative stress is implicated in some forms of delayed radiation injury, we are investigating whether these compounds can mitigate injury to normal tissues caused by ionizing radiation. This review describes ...

Synthetic routes to a series of new (salen-1)CoX (salen-1 = N,N'-bis(salicylidene)-1,2-diaminoalkane; X = halide or carboxylate) species are described and the X-ray crystal structures of two (salen-1)CoX (salen- = N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-diaminocyclohexane; X = Cl, I) complexes are presented. (R,R)-(salen-)CoX (X = Cl, Br, I, OAc, pentafluorobenzoate (OBzF(5))) catalysts are...

We analyzed the apoptosis and anti-tumour activities of several Mn(III)-salen and -salphen complexes (1-14) towards three different cultured human cancer and non-cancer cells. We demonstrated that most of the Mn(III)-salen and -salphen complexes affect cell viability and induce apoptosis in MCF7 cells. Biochemically active Mn(III)-salen and -salphen complexes induced nuclear fragmentation and r...

The first immobilization of a pyrene-tagged chromium salen complex through π-π noncovalent interactions on reduced graphene oxide (rGO) is described. A very robust supported catalytic system obtained to promote asymmetric catalysis in repeated cycles, without loss activity or enantioselectivity. This specific behavior was demonstrated two different reactions (up ten reuses) promoted by complexe...

Biodegradable polymers are a promising sustainable alternative to conventional petroleum-based and have attracted recent extensive research interest due their potential environmental friendliness sustainability. Among them, aliphatic polyesters polycarbonates the most extensively studied ones. The metal-catalyzed ring-opening polymerization (ROP) of cyclic esters copolymerization (ROCOP) epoxid...

We have successfully prepared an unsymmetrical analogue of a Katsuki-type salen ligand having a single hydroxyalkyl group at its 6-position, and also its Mn(III) complex; attachment of the complex to a polymer gives a highly enantioselective and recoverable catalyst for epoxidation of 1,2-dihydronaphthalene.