Tissue-engineering technologies have progressed rapidly through last decades resulting in the manufacture of quite complex bioartificial tissues with potential use for human organ and tissue regeneration. The manufacture of avascular monolayered tissues such as simple squamous epithelia was initiated a few decades ago and is attracting increasing interest. Their relative morphostructural simpli...

The placenta facilitates nutrient and gas exchanges between the mother and growing fetus. It does this through highly branched embryonic blood vessels called villi. In the mouse, villi start to form when the allantois attaches to the chorion. This attachment is mediated through a thin layer of mesothelium on the chorion, which becomes indistinguishable from the allantoic cells after attachment....

BACKGROUND Malignant mesothelioma is a malignancy with a primary resistance to chemo- and radiotherapies for reasons which are still unclear. Multidrug resistance proteins might explain the observed resistance, but no studies have assessed their expression in mesothelioma. PATIENTS AND METHODS Immunohistochemical expression of P-glycoprotein (P-gp), and the multidrug resistance proteins 1 and...

High-grade serous ovarian carcinoma (HGS-OvCa) harbors p53 mutations and can originate from the epithelial cell compartment of the fallopian tube fimbriae. From this site, neoplastic cells detach, survive in the peritoneal cavity, and form cellular clusters that intercalate into the mesothelium to form ovarian and peritoneal masses. To examine the contribution of mutant p53 to phenotypic altera...

The current study was designed to identify the histological composition of ileum in Caucasian squirrel Sciurus anomalus. Ten adult squirrels were used for present study. Animals anesthetized, anatomized, fixed specimens 10% formalin solution, and conducted a series staining techniques. consists four main tunicae represented by mucosa, submucosa, muscularis, serosa. tunica mucosa three secondary...

In the United States, invasive ovarian cancer is the 5th most deadly malignancy in females, accounting for an estimated 13,850 deaths in 2010 (Ahmad, 2011; American Cancer Society, 2010). The risk of dying from ovarian cancer depends on staging and varies greatly. Ovarian cancer patients diagnosed at the localized stage exhibit a 5 year survival rate of 94%. This rate is 73% when diagnosed at t...

The yolk sac of human embryos from the 5th to 7th week of gestation was first revealed under the scanning electron microscope (SEM) with complementary observations under the transmission electron microscope (TEM). The inner and outer surfaces of the human yolk sac basically showed profiles similar to those of other mammalian yolk sacs reported by previous workers. The free surface of the endode...