The question of which acquisition parameters govern long-term retention is important to an understanding of memory function. We investigate the effects of the time interval between learning trials on mediate (1 day)- and long-term (4 days) retention. In classical conditioning of the proboscis extension reflex, we train honeybees to associate an odorant with a sucrose reward using intertrial int...

The charge retention characteristics of metal nanocrystal (MNC) and semiconductor nanocrystal (SNC) memory devices are comparatively studied in this paper. A charge retention model is proposed, taking into account the quantum confinement effect, to account for the better retention characteristics of metal nanocrystal memory observed in the experiment. Simulation results are in good agreement wi...

Accelerated long-term forgetting (ALF) is a form of memory impairment in which learning and initial retention of information appear normal but subsequent forgetting is excessively rapid. ALF is most commonly associated with epilepsy and, in particular, a form of late-onset epilepsy called transient epileptic amnesia (TEA). ALF provides a novel opportunity to investigate post-encoding memory pro...

Considerable evidence implicates glucocorticoid hormones in the regulation of memory consolidation and memory retrieval. The present experiments investigated whether the influence of these hormones on memory depends on the level of emotional arousal induced by the training experience. We investigated this issue in male Sprague-Dawley rats by examining the effects of immediate posttraining syste...

Former students (N = 373) of a course in cognitive psychology (CP), conducted between 1978 and 1989, completed memory tests to assess retention of CP. Memory for proper names of researchers, concepts, and conceptual relations varied with retention interval (RI), and memory performance declined over the first 36 months of retention and then stabilized at above-chance levels for the remainder of ...

vii Chapter One: Introduction 1 Hippocampus, Neuronal Atrophy and Memory 1 Stress, Corticosterone and Synaptic Plasticity 4 Current Stress and Working Memory Research 6 Tianeptine, Serotonin, NMDA and Memory 8 The Beta-Adrenergic System and Propranolol 9 Adrenalectomy and Memory 12 Current Experiments 16 Chapter Two: Experiment One: Tianeptine Blocks Stress-Induced Memory Errors on the Criterio...

Here we show that a systemic injection of the histone deacetylase inhibitor (HDACi) sodium butyrate (NaB) immediately after training in a step-down inhibitory avoidance task produced an enhancement of memory consolidation that persisted across consecutive retention tests during 14 days in aged rats, while it did not significantly affect memory in young adults. Control aged and young adult rats ...

BACKGROUND Verbal memory is frequently and severely affected in schizophrenia and has been implicated as a mediator of poor clinical outcome. Whereas encoding deficits are well demonstrated, it is unclear whether retention is impaired. This distinction is important because accelerated forgetting implies impaired consolidation attributable to medial temporal lobe (MTL) dysfunction whereas impair...

Observers made change-detection judgments for colored squares in a paradigm that manipulated the retention interval, the magnitude of change, and objective change probability. The probability of change judgments increased across the retention interval for “same” and “small-change” test items but stayed the same or decreased for “large-change” and “far” test items. A variety of formal models wer...

PURPOSE Despite their excellent clinical validity, objective measures of memory often do not reflect self-perceived memory impairment. This discordance has mostly been attributed to depressed mood. Alternatively, a lack of ecological validity due to the rather short standard retention intervals of 20-60 min may be responsible for this discordance. Therefore, we explored the value of extended re...