BACKGROUND Longitudinal melanonychia (LM) can be a challenging sign since it may be caused by a wide variety of benign and malignant conditions. Cutaneous melanoma is the most important cause of LM. Objective: We performed this study to examine different aspects of LM in Iran, where cutaneous melanoma is rare. METHODS In this cross-sectional study, we reviewed medical records and pathology re...

We present the case of a 48-year-old-woman from Ecuador who was diagnosed with systemic lupus erythematosus in March 2004 based on symmetric polyarthritis which affected the wrists and small joints of the hands, as well as oral ulcers, Coombspositive hemolytic anemia, leukopenia and positive antinuclear, anti-DNA, anti-Sm, antiribonucleoprotein, anti-Ro/SSA and IgM and IgG anticardiolipin antib...

To the Editor: Differentiating nail matrix nevus (NMN) from subungual melanoma on clinical grounds is challenging, especially in children, because their NMNs may mimic features of melanoma.1Cooper C. Arva N.C. Lee et al.A clinical, histopathologic, and outcome study melanonychia striata childhood.J Am Acad Dermatol. 2015; 72: 773-779Abstract Full Text PDF PubMed Scopus (47) Google Scholar, 2Ohn...

Results A total of 88 subjects were examined (45men and 43 women); the average age were 41 years old. Abnormal appearing nails were present in 48 cases. Mycologic evidence of onychomycosis were present in 42 cases. The clinical presentation of onychomycosis was: distal and lateral subungual onychomycosis (47%); white superficial onychomycosis (5%); proximal subungual onychomycosis (21%); total ...

OBJECTIVES To study the frequency of nail changes in a population of human immunodeficiency virus (HIV)-infected patients and to evaluate the specificity of these findings by comparison with HIV-negative control subjects. DESIGN Prospective controlled study. Nail changes were recorded by a standardized clinical examination (curvature, nail plate, color, onychomycosis). In case of clinical dia...

5-FU: 5-fluorouracil FOLFIRI: 5-fluorouracil, irinotecan, and folinic acid TEC: toxic erythema of chemotherapy INTRODUCTION Here we describe a case of systemic FOLFIRIassociated balanitis successfully treated by topical steroids, without discontinuation of chemotherapy treatment. FOLFIRI consists of the pyrimidine analog antimetabolite, 5-fluorouracil (5-FU), the topoisomerase inhibitor, irinot...