نتایج جستجو برای: mef

تعداد نتایج: 1416  

Journal: :Molecular pharmacology 2008
Z Ping Lin Yong-Lian Zhu Dennis R Johnson Kevin P Rice Timothy Nottoli Bryan C Hains James McGrath Stephen G Waxman Alan C Sartorelli

Multidrug resistance protein 4 (MRP4; ABCC4) is a member of the MRP/ATP-binding cassette family serving as a transmembrane transporter involved in energy-dependent efflux of anticancer/antiviral nucleotide agents and of physiological substrates, including cyclic nucleotides and prostaglandins (PGs). Phenotypic consequences of mrp4 deficiency were investigated using mrp4-knockout mice and derive...

2014
Dodi Safari Lu-Cheng Kuo Yu-Tsung Huang Chun-Hsing Liao Wang-Huei Sheng Po-Ren Hsueh

BACKGROUND This study investigated the molecular characteristics of azithromycin-resistant Streptococcus pneumoniae in Taiwan. METHODS A total of 486 non-duplicate isolates of azithromycin-resistant S. pneumoniae recovered from various clinical sources of patients treated at 22 different hospitals in Taiwan from 2006 to 2010. The presence of erm(B) and mef(A) genes using duplex PCR, multilocu...

Journal: :Journal of cell science 2007
Marko Jović Naava Naslavsky Debora Rapaport Mia Horowitz Steve Caplan

beta1 integrins bind to the extracellular matrix and stimulate signaling pathways leading to crucial cellular functions, including proliferation, apoptosis, cell spreading and migration. Consequently, control of beta1 integrin function depends upon its subcellular localization, and recent studies have begun to unravel the complex regulatory mechanisms involved in integrin trafficking. We report...

2017
M. A. Nosenko N. V. Maluchenko M. S. Drutskaya A. Y. Arkhipova I. I. Agapov S. A. Nedospasov M. M. Moisenovich

Culturing of allogeneic or autologous cells in three-dimensional bioresorbable scaffolds is an important step in the engineering of constructs for regenerative medicine, as well as for experimental systems to study the mechanisms of cell differentiation and cell-to-cell interaction. Artificial substrates can modulate the phenotype and functional activity of immobilized cells. Investigating thes...

2016
Namchul Jo Jongnam Kim Seongwon Seo

The methodology provided by the Intergovernmental Panel on Climate Change (IPCC) guidelines is widely used for estimating enteric methane (CH4) production by cattle. No attempt other than the default values in the IPCC Tier 1 has been made for estimating CH4 emission from Hanwoo, a dominant beef species in Korea raised in a unique feeding system. The objective of this study was to compare model...

Journal: :Animal reproduction science 2000
J S Park Y M Han C S Lee S J Kim Y H Kim K J Lee K S Lee K K Lee

The in vitro development of DNA-injected bovine zygotes, produced in vitro, was compared when cultured with or without mouse embryonic fibroblasts (MEF). The in vivo viability of the embryos produced in these in vitro culture systems was assessed by single or double transfer to recipients taken to term. For these experiments, in vitro fertilized oocytes were not injected (Experiment 1) or were ...

Journal: :Journal of clinical microbiology 2007
Yongwei Cai Fanrong Kong Gwendolyn L Gilbert

Streptococcus agalactiae (group B streptococcus [GBS]) is the most common cause of neonatal sepsis (9). Penicillin is used for intrapartum prophylaxis, but erythromycin or clindamycin is recommended for patients allergic to penicillin (3). There are two major mechanisms of erythromycin resistance in S. agalactiae, (i) erythromycin ribosomal methylase, mediated by ermB, ermA, ermTR, or ermC, whi...

Journal: :Phytomedicine : international journal of phytotherapy and phytopharmacology 2010
M H Boskabady N Mohsenpoor L Takaloo

In the present study, the antiasthmatic (bronchodilatory) effect of the boiled extract of Nigella sativa in the airways of asthmatic patients was examined. The bronchodilatory effects of 50 and 100 mg/kg of boiled extract in comparison with 6 mg/kg theophylline were studied on 15 asthmatic patients. Pulmonary function tests (PFTs) including forced expiratory volume in one second (FEV(1)), peak ...

Journal: :Journal of environmental monitoring : JEM 2011
Willians Llanos David Kocman Pablo Higueras Milena Horvat

The laboratory flux measurement system (LFMS) and dispersion models were used to investigate the kinetics of mercury emission flux (MEF) from contaminated soils. Representative soil samples with respect to total Hg concentration (26-9770 μg g(-1)) surrounding a decommissioned mercury-mining area (Las Cuevas Mine), and a former mercury smelter (Cerco Metalúrgico de Almadenejos), in the Almadén m...

Journal: :Physics of Fluids 2023

The use of alternative extraction methods has increased since conventional have disadvantages like long processing time and limited yield. It is known that the yield enhanced, shortened by electric field. However, mathematical characterization electrically assisted processes needed for a better understanding improvement extraction. In this study, effects moderate field (MEF-E) parameters (frequ...

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