نتایج جستجو برای: meconium

تعداد نتایج: 2183  

2006
Janine Hutson

easurement of fatty acid ethyl esters (FAEE) in meconium is a relatively novel biomarker to detect heavy prenatal alcohol exposure. As a biomarker of exposure, FAEEs have been shown to have high sensitivity and specificity. Recent studies have also evaluated the ability of FAEEs in meconium to predict adverse outcomes associated with fetal alcohol spectrum disorder (FASD). This article will rev...

Journal: :Clinical chemistry 1995
C Moore D Lewis J Leikin

To determine the number of false-negative results produced by inefficient extraction of drugs from meconium, three published procedures were compared by using previously confirmed positive and negative meconium specimens. The methods were not equivalent in their ability to extract drugs from the matrix. To determine the number of false positives reported by the use of screen-only (unconfirmed) ...

ژورنال: پژوهش در پزشکی 2008
دکتر آذر زمانی, , دکتر ناهید عباسی, , دکتر ناهید مستقل, ,

Background and Aim: Puerperal infection describes any bacterial infection of the genital tract after delivery. It is the cause of 13% of pregnancy related deaths and the fifth leading cause of death. Some studies have addressed the role of meconium-stained amniotic fluid in puerperal infection. The aim of this study was to evaluate the association between meconium-stained amniotic fluid and pue...

Journal: :The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 2009
Simona Pichini Luca Morini Emilia Marchei Ilaria Palmi Maria Concetta Rotolo Federica Vagnarelli Oscar Garcia-Algar Oriol Vall Piergiorgio Zuccaro

BACKGROUND In recent years, fatty acid ethyl esters (FAEEs) in meconium emerged as reliable, direct biological markers for establishing gestational ethanol exposure. Among the minor nonoxidative products of ethanol metabolism, there are ethyl glucuronide (EtG) and ethyl sulfate (EtS). OBJECTIVES The aim of the study was to analyse meconium specimens from two different Mediterranean cohorts to...

Journal: :Clinical chemistry 2003
Christine Moore Joseph Jones Douglas Lewis Karen Buchi

BACKGROUND Fetal alcohol syndrome (FAS), alcohol-related birth defects (ARBDs), and alcohol-related neurodevelopment disorders (ARNDs) in neonates are often the result of maternal alcohol consumption during pregnancy. Facial characteristics are associated with FAS, but ARBDs and ARNDs are more difficult to diagnose. Fetal exposure to alcohol can cause central nervous system dysfunction, pre- an...

Journal: :The Journal of clinical investigation 2013
David A Stoltz Tatiana Rokhlina Sarah E Ernst Alejandro A Pezzulo Lynda S Ostedgaard Philip H Karp Melissa S Samuel Leah R Reznikov Michael V Rector Nicholas D Gansemer Drake C Bouzek Mahmoud H Abou Alaiwa Mark J Hoegger Paula S Ludwig Peter J Taft Tanner J Wallen Christine Wohlford-Lenane James D McMenimen Jeng-Haur Chen Katrina L Bogan Ryan J Adam Emma E Hornick George A Nelson Eric A Hoffman Eugene H Chang Joseph Zabner Paul B McCray Randall S Prather David K Meyerholz Michael J Welsh

Cystic fibrosis (CF) pigs develop disease with features remarkably similar to those in people with CF, including exocrine pancreatic destruction, focal biliary cirrhosis, micro-gallbladder, vas deferens loss, airway disease, and meconium ileus. Whereas meconium ileus occurs in 15% of babies with CF, the penetrance is 100% in newborn CF pigs. We hypothesized that transgenic expression of porcine...

2014
Shannon Lange Kevin Shield Gideon Koren Jürgen Rehm Svetlana Popova

BACKGROUND Maternal self-reports, used for the detection of prenatal alcohol exposure (PAE), may lack validity, necessitating the use of an objective biomarker. The detection of fatty acid ethyl esters (products of non-oxidative ethanol metabolism) in meconium has been established as a novel biomarker of PAE. The purpose of the current study was to compare the prevalence of PAE as reported via ...

2013
Philemon E Okoro Cosmos E Enyindah

INTRODUCTION The first stool passed by the newborn, the meconium, is different from the ordinary stool both in its nature and its implication. Delayed or non-passage of the meconium may represent a number of clinical conditions. In this study, we sought to identify what should be considered delayed passage of meconium in our babies. AIMS AND OBJECTIVES To investigate the timing of passage of ...

2015
Hae-Young Kim Soo-Hong Kim Yong-Hoon Cho Shin-Yun Byun Young-Mi Han Ah-Young Kim

PURPOSE One of the major causes of bowel obstruction in extremely premature infants is a meconium obstruction. However, there are many challenges not only in the recognition and diagnosis, but also in the management of meconium obstruction. This study aimed to find perioperative clinical features and determine the postoperative course of meconium-related ileus in very low birth weight (VLBW) an...

Journal: :Journal of pediatric surgery 2001
S J Han A Han S H Choi J T Oh E H Hwang

BACKGROUND/PURPOSE This report describes our experiences with 5 cases of biliary atresia associated with meconium peritonitis caused by perforation of small bowel atresia. METHODS A review of medical records was undertaken in an effort to recognize cases of biliary atresia associated with meconium peritonitis. RESULTS Five patients of 171 with biliary atresia (2.9%) were detected to have me...

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