Gamma interferon (IFN-γ) plays an important role in the immune response to live measles virus vaccination. To study the immune response to measles vaccination, IFN-γ level was estimated in 30 children. Of these, 24 children vaccinated with a single dose of measles vaccine at nine months of age and 06 children vaccinated with a second dose during the Measles Catch-up Immunization campaign. Measl...

OBJECTIVE To quantify the impact on mortality of offering a hypothetical set of technically feasible, high-impact interventions for maternal and child survival during India's 2010-2013 measles supplementary immunization activity. METHODS We developed Lives Saved Tool models for 12 Indian states participating in the supplementary immunization, based on state- and sex-specific data on mortality...

Since the first isolation of measles virus in human and monkey renal cells by Enders and Peebles (1), the virus has been grown in primary cultures of human amnion (5, 6), chick en\.bryo (3), dog kidney (2), bovine kidney (4,8), and guinea pig kidney (9). Sorne of these tissues have now even been employed for the production of measles vaccine. This report presents our data indicating the high su...

BACKGROUND: Although an effective measles vaccine has been available for almost 40 years, in 2000 there were about 30 million measles infections worldwide and 777,000 measles-related deaths. The history of smallpox suggests that achieving measles eradication depends on several factors; the biological characteristics of the organism; vaccine technology; surveillance and laboratory identification...

BACKGROUND Measles virus, member of the genus Morbillivirus in the family Paramyxoviridae, is a highly contagious human pathogen. An effective live-attenuated vaccine is available and its use has the potential to eradicate the disease from the human population. Although the vaccine was introduced in national vaccination schedules, several measles outbreaks have occurred because of insufficient ...

abstract: measles remains one of the leading causes of childhood morbidity and mortality in developing countries and is still a major public health concern in developed countries. although live attenuated vaccine is used throughout the world, out breaks of disease still occur in many countries including iran. understanding measles outbreaks that occur after the initiation of measles elimination...

Measles remains an important cause of childhood mortality worldwide. Sustained high vaccination coverage is the key to preventing measles deaths. Because measles vaccine is delivered by injection, hurdles to high coverage include the need for trained medical personnel and a cold chain, waste of vaccine in multidose vials and risks associated with needle use and disposal. Respiratory vaccine del...

OBJECTIVE To develop a model for identifying areas at high risk for sporadic measles outbreaks based on an analysis of factors associated with a national outbreak in South Africa between 2009 and 2011. METHODS Data on cases occurring before and during the national outbreak were obtained from the South African measles surveillance programme, and data on measles immunization and population size...

I read with interest and curiosity the Viewpoint and IAPCOI stand articles on AEFI with particular reference to measles vaccination related deaths in Tamil Nadu(1,2). I want to share my personal experience as a field investigator on similar measles vaccination deaths in Manali New town PHC (about 10 km from Chennai) way back in 1991-1992. At that time 6 children died. All of them developed high...

• Vol 10 • August-September 2008 640 Measles is still a significant cause of morbidity and mortality in children in the Middle East. This region has many hard-to-reach populations, causing difficulties in the provision of adequate immunization coverage. There has been concern that measles vaccine may produce transient immunosuppression in malnourished children and thereby increase their risk fo...