The pharmacokinetics and tolerability of nebulized MP-376 (levofloxacin inhalation solution [Aeroquin]) were determined in cystic fibrosis (CF) subjects. Ten CF subjects received single 180-mg doses of two formulations of MP-376, followed by a multiple-dose phase of 240 mg once daily for 7 days. Serum and expectorated-sputum samples were assayed for levofloxacin content. Safety was evaluated fo...

drought stress is considered as the most important environmental abiotic stress, affecting grain yield of crop plants especially in arid and semi arid regions. increasing and utilization of the genetic diversity can be a useful strategy in breeding for drought resistance. in this study, twenty iranian durum wheat landraces along with two check cultivars were evaluated in a randomized complete b...

PURPOSE The three carotenoids lutein, zeaxanthin, and meso-zeaxanthin, are found at the macula and referred to as macular pigment (MP). This study was undertaken to investigate determinants of MP in a large randomly selected sample from the Republic of Ireland (as part of The Irish Longitudinal Study on Ageing [TILDA]). METHODS MP optical density (MPOD) was measured using customized heterochr...

PURPOSE Macular pigment (MP) may protect against age-related macular degeneration. This study was conducted to determine the extent of changes in the macular pigment density as a consequence of oral supplementation with lutein. A second purpose was to compare two objective measurement techniques. METHODS In the first technique, reflectance maps were made with a scanning laser ophthalmoscope. ...

Articular eminence inclination (AEI) of the temporomandibular joint leads the mandible in its movements. Therefore, the aim of the present study was to determine AEI values in medieval (MP) and recent (RP) Croatian population. The study was carried out on two groups of specimens: first group with 30 MP human dry skulls, while the other, serving as control group consisted of 137 dry skulls. The ...

The aim of this study was to increase the understanding of the mechanisms regulating cell proliferation and recombinant protein production in serum-free cultures of Trichoplusia ni (T. ni) insect cells. Conditioned medium (CM) was shown to contain both stimulatory and inhibitory factors (CM factors) influencing cell growth. Metalloproteinase (MP) activity was the major factor responsible for th...

The main objective of this research was to evaluate fifteen durum wheat (Triticum durum) genotypes selected from joint project of Iran/ICARDA for drought tolerance using several indices. The trials were conducted under moderate levels of drought stress for three cropping seasons (2004-2006) in four locations in the highlands western of Iran. The combined ANOVA for grain yield over years and loc...

PURPOSE To investigate the relationship between specific macular pigment (MP) spatial profiles and risk factors for age-related macular degeneration (AMD). METHODS The MP spatial profile of 484 healthy subjects was measured with customized heterochromatic flicker photometry (cHFP) and categorized into one of two profile types: typical exponential or atypical "central dip." Data on risk factor...