Neonatal sepsis is a significant health issue associated with high mortality. Immune responses associated with neonatal sepsis, such as proinflammatory cytokine production, are believed to play a central role in the pathogenesis of this disease. In the present study, serum levels of the proinflammatory cytokines TNF-α, IL1-β, and IL-6 and the anti-inflammatory cytokines IL-4 and IL-10 were eval...

Infection in neonates, particular the neonatal sepsis continues to be a global problem with significant morbidity and mortality. The diagnosis of neonatal sepsis is complicated by nonspecific clinical symptomatology, a high-false negative rate, and a delay in obtaining blood culture results. MicroRNAs (miRNAs) have recently been used as finger prints for sepsis, and have been validated to be po...

Background Neonatal sepsis is a critical condition caused by a generalized bacterial infection in the first month of life. The present study aimed to investigate the relationship between serum vitamin D levels and neonatal sepsis. Materials and Methods: A search of online databases (Medl...

Neonatal sepsis is a common cause of neonatal morbidity and mortality in developing countries. It is a serious bacterial infection of blood with a clinical syndrome characterized by systemic signs of infection and bacteremia in the first month of life. Factors associated with positive blood culture and perinatal deaths among neonates are rarely described in developing countries. This study aime...

BACKGROUND It has recently been suggested that serum procalcitonin (PCT) is of value in the diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to assess the usefulness of PCT as a marker of neonatal sepsis of nosocomial origin. METHODS One hundred infants aged between 4 and 28 days of life admitted to the Neonatology Services of 13 acute-care...

OBJECTIVE To evaluate the prevalence factors and etiologies associated with late neonatal sepsis in preterm neonates in a neonatal intensive care unit. METHODS This was a cross-sectional study of secondary data pertaining to preterm neonates admitted to the neonatal intensive care unit between 2008 and 2010 and was gathered from medical charts. The outcome variable, late neonatal sepsis, was ...

Introduction: Unique aspects of neonatal renal physiology enhance the occurrence Acute Kidney Injury (AKI) as a complication sepsis. The study sought to determine prevalence AKI and its characteristics in neonates with suspected sepsis.
 Methods: A cross-sectional was conducted at Kenyatta National Hospital among aged 0-28 days. defined serum creatinine more than 100μmmol/l.
 Results:...

UNLABELLED Group B Streptococcus is the most common pathogen found in neonatal sepsis in North America. OBJECTIVES We describe 15 cases of neonatal infections by Group B Streptococcus (Streptococcus agalactiae) at a Neonatal Intensive Care Unit of a public and teaching hospital. METHODS We conducted a study at Hospital de Clínicas de Porto Alegre, from January 1st, 1996 to June 30, 1999. Di...

Introduction Neonatal sepsis is a leading cause of neonatal mortality and morbidity in the world. The objective of the current study was to detect the common causative microorganisms of neonatal sepsis and their antimicrobial resistance patterns in a rural secondary hospital in Tamil Nadu, India. Materials and Methods Neonates (0-28 days) admitted to this newborn care unit from October 2013 t...