Osteopetrosis, also known as marble bone disease, is a clinically rare genetic disease, which represents a heterogeneous group of rare, inherited bone dysplasias that share the hallmark of abnormally increased bone density caused by osteoclast dysfunction. Hereby, the authors describe a case of osteopetrosis that showed increased diffuse radioactive uptake on whole body bone Tc-methylene diphos...

chronic recurrent multifocal osteomyelitis (crmo) is an inflammatory bone disease usually affecting children. a 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. in every time, symptoms vanished after several weeks. the patient received antibiotics only in one period of bone pain. in other occasions the patient didn’t received any antibiotics. ...

Lipopolysaccharide (LPS) is bacterial cell wall component capable of inducing osteoclast formation and pathological bone resorption. Muramyl dipeptide (MDP), the minimal essential structural unit responsible for the immunological activity of peptidoglycans, is ubiquitously expressed by bacterium. In this study, we investigated the effect of MDP in LPS-induced osteoclast formation and bone resor...

Received 10/2/2000; revised 11/17/2000; accepted 12/2/2000. For correspondence or reprints contact: Ming-Che Wu, M.D., Department of Nuclear Medicine, MacKay Memorial Hospital, 92, Section 2, Chung-San North Road, Taipei 10449, Taiwan. Tel: (886)2-25433535 ext. 3369, Fax: (886)2-25433535 ext. 2925, E-mail: [email protected] Background: The authors evaluated the performance of Tc-MDP planar sk...

markedly elevated111 in labeled leukocyte activity suggestive of acute osteomyelitis was observed in a region of a composite mandibular allograft that was photon deficient on 99mtc mdp bone scintigraphy. this finding was later confirmed by surgical pathology. the patient was treated with intravenous antibiotics and returned two months later with persistent bone infection. the fohow-up three pha...

Stanford University, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, USA Here we prospectively compared the combined 18F NaF/18F FDG PET/ MRI against 99mTc-MDP in patients with breast and prostate cancers. Twelve patients referred for 99mTc-MDP bone scans were prospectively enrolled from Oct 14 Jan 15. The cohort included 6 men with prostate cancer and 6 women with ...

Received 8/9/2000; accepted 8/30/2000. For correspondence or reprints contact: Shyh-Jen Wang, M.D., Department of Nuclear Medicine, Taichung Veterans General Hospital, 160, Sec. 3, Taichung Harbor Road, Taichung 407, Taiwan, R.O.C. Tel: (886)4-23741349, Fax: (886)4-23741348, E-mail: [email protected] Adamantinoma is a rare low-grade malignant lesion that shows both epithelial and mesenc...