نتایج جستجو برای: maternal blood pressure

تعداد نتایج: 1055563  

2008
Ruth Andrew Janet W. Rich-Edwards Ken P. Kleinman Jonathan R. Seckl Matthew W. Gillman Susanna Y Huh Janet W Rich-Edwards Ken P Kleinman Jonathan R Seckl Matthew W Gillman

Background: Animal data show that decreased activity of placental 11-beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), which potently inactivates glucocorticoids (e.g. cortisol) to inert forms (cortisone), allows increased access of maternal glucocorticoids to the fetus and 'programs' hypertension. Data in humans are limited. We examined in humans the association between venous umbilical cor...

2011
Olena Rudyk Péter Makra Eugene Jansen Michael J. Shattock Lucilla Poston Paul D. Taylor

Diet-induced obesity in rat pregnancy has been shown previously to be associated with consistently raised blood pressure in the offspring, attributed to sympathetic over-activation, but the relative contributions to this phenotype of maternal obesity versus raised dietary fat is unknown. Sprague-Dawley female rats were fed either a control (4.3% fat, n = 11) or lard-enriched (23.6% fat, n = 16)...

2013
Jumana Saleh Lovina Machado Zahra Razvi

INTRODUCTION Increased neonatal birth weight (NBW), often associated with diabetic pregnancies, is a recognized indicator of childhood obesity and future metabolic risk. Predictors of NBW in healthy non-diabetic pregnancies are not yet established. Here, we investigated the association of maternal parameters of healthy non-diabetic mothers with NBW of their "appropriate-for-gestational age" neo...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2008
K A Brennan S Kaufman S W Reynolds B T McCook G Kan I Christiaens M E Symonds D M Olson

The mechanisms whereby maternal nutritional manipulation through pregnancy result in altered blood pressure in the offspring may include changes in fetal and newborn and adult renal prostaglandin (PG) synthesis, metabolism, and receptor expression. Since the postnatal effects of nutrient restriction on the renal PG synthesis and receptor system during nephrogenesis in conjunction with nephron n...

2017
Jian Ding Yan Kang Yuqin Fan Qi Chen

OBJECTIVE Preeclampsia (PE) is a complication affecting pregnant women worldwide, which usually manifests as severe maternal hypertension. Resveratrol (RESV), a naturally existing polyphenol, is known to exhibit beneficial effects in cardiovascular disease including hypertension. We evaluated the outcome of treatment combining oral nifedipine (NIFE) and RESV against PE. DESIGN AND METHODS Usi...

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