Transplacental passage of circulating first-trimester fetal mesenchymal stem cells (fMSC) raises the prospect of harvesting fetal cells in maternal blood. Despite high sensitivity in model systems, negative selection and culture strategies yield fMSC only rarely in post-termination maternal blood. The different adhesion molecule profile of fMSC to competitor maternal cell types suggests that im...

background: fetal dna in maternal plasma and serum has been shown to be a useful material for prenatal fetal sex determination during early gestational ages. non-invasive prenatal diagnosis is now possible at 8th week of pregnancy, by maternal blood sample testing. objective: the purpose of this study was to evaluate two dna extraction methods from mother plasma and its routine clinical applica...

Pregnant ewes and their fetuses were instrumented between 110 to 120 days of gestation (term, 145 days) for monitoring heart rate, blood pressure, uterine artery blood flow, and fetal intra-abdominal umbilical artery blood flow and arterial blood gases. DOM (2,5-dimethoxy-4methyl-amphetamine) was administered intravenously to the ewe in doses of 1, 2.5, 5, 10, or 20 fig/kg. Maternal administrat...

BACKGROUND Cell salvage has been used in obstetrics to a limited degree because of a fear of amniotic fluid embolism. In this study, cell salvage was combined with blood filtration using a leukocyte depletion filter. A comparison of this washed, filtered product was then made with maternal central venous blood. METHODS The squamous cell concentration, lamellar body count, quantitative bacteri...

BACKGROUND Few data exist on the intergenerational influence of calcium intake during pregnancy on offspring blood pressure. METHODS AND RESULTS As part of the ongoing US prospective cohort study Project Viva, we analyzed 4091 Dinamap blood pressure measurements from 936 six-month-old infants whose mothers had completed food frequency questionnaires during the second trimester of pregnancy. W...

Background: 79% of the pregnant women suffer from sleep disorders. These disorders are the result of physiological, hormonal, physical changes, that occur in pregnancy due to different causes including fetal sex and maternal blood group. This study aimed to evaluate the relationship between fetal sex and maternal blood group with sleep disorders during pregnancy in the second and third trimeste...

Introduction:Maternal diabetes mellitus is associated with depleted fetal iron stores and this is proportionate to the degree of maternal control, presence or absence of diabetes-related complications, and is not related to maternal iron status. In this study, we aim to assess the effect of maternal diabetes on cord blood serum ferritin. Methods: The present prospective (case-control) study was...

Background: Postpartum hemorrhage (PPH) is a leading cause of severe maternal morbidity and mortality worldwide which leads to massive blood loss. Coagulation abnormalities in response trauma or infection are latent that might aggravate PPH.

Pregnancy has commonly been viewed as a cooperative interaction between a mother and her fetus. The effects of natural selection on genes expressed in fetuses, however, may be opposed by the effects of natural selection on genes expressed in mothers. In this sense, a genetic conflict can be said to exist between maternal and fetal genes. Fetal genes will be selected to increase the transfer of ...

BACKGROUND The influence of multiple maternal and pregnancy characteristics on offspring cardiometabolic traits at birth is not well understood and was evaluated in this study. METHODS AND FINDINGS The Family Atherosclerosis Monitoring In earLY life (FAMILY) Study prospectively evaluated 11 cardiometabolic traits in 901 babies born to 857 mothers. The influence of maternal age, health (pre-pr...