Ag encounter will recruit Ag-specific cells from the pool of mature B lymphocytes in the spleen and activate them to perform effector functions: generation of Ab-forming cells (plasma cells) and presentation of Ag to T cells. We have compared the ability of mature follicular and marginal zone cells to develop into effector B cells. The generation of marginal zone B cells and their localization ...

A wide array of field observations, in situ testing, and rock and water sampling (and subsequent analyses) within the unsaturated zone (UZ) of Yucca Mountain demonstrate the importance of fractures to flow and transport in the welded tuffs. The abundance of fractures and the spatial variability in their hydraulic properties, along with the heterogeneity within lithologic formations, make evalua...