Screening of latent infection by Mycobacterium tuberculosis (LTBI) and treatment of positive subjects is the key point in the prevention of TB; such a strategy should be performed mainly among individuals with risk of progression. Progression from LTBI to active TB is highest both in recent contacts of patients with active TB, and in immunocompromised subjects. Therefore, LTBI could either be c...

Snow banking is usually a term coined to describe the accumulation of vitreous exudates over the pars plana and the peripheral retina in pars planitis. Snow banking is very rare in tubercular intermediate uveitis. A 32-year-old male was diagnosed to have intermediate uveitis due to tubercular etiology in the right eye. Laboratory investigations include an increased erythrocyte sedimentation rat...

erythrocyte sedimentation rate was 30mm. Antinuclear antibodies, rheumatoid factor, and serological tests for cytomegalovirus, herpes simplex virus types 1 and 2, hepatitis B and C viruses, human immunodeficiency virus (HIV), Toxoplasma gondii, Bartonella henselae, Salmonella typhi, Brucella, Leptospira, and Francisella tularensis were negative. Serological tests were positive for Epstein-Barr ...

A hospital-based case control study was carried out to determine the pattern of infections and immunoblobulin levels in Sudanese children with severe protein energy malnutrition (PEM). The pre-dietary rehabilitation levels of the three major immunoglobulins (IgG, IgA and IgM) were compared with those of normal controls, and with the levels after dietary rehabilitation. Eighty one children were ...

OBJECTIVE To identify the clinical pattern of symptomatic ocular tuberculosis (OTB) and the outcome following antitubercular therapy (ATT) in an endemic setting. DESIGN A descriptive case series. SETTING Tuberculosis and ophthalmology clinics, Teaching Hospital, Kandy, Sri Lanka. METHOD We followed up patients with OTB on standard six-month regimen of ATT, from January 2006 to December 20...

miparous, came to our clinic at 4 months postpartum with a 3-month history of a painful swelling in her left breast. It had already been drained on several occasions. She had no history of fever, trauma or use of oral contraceptives; her family history was positive for breast cancer. A physical examination revealed ulcerated peau d’orange skin (Fig. 1) above a firm, tender, 8–10 cm mass with an...

Previous investigations of immune function in patients with Crohn's disease have yielded conflicting results. A comprehensive study of immune competence-peripheral lymphocyte count, serum immunoglobulin levels (IgG, IgA and IgM), lymphocyte response to PHA, Mantoux test, and DNCB response-has been performed in a large number of patients with inflammatory bowel disease. A total of 52 patients wi...

Using an autologous system, suppressor cell function to a range of mycobacterial antigens and Kunin antigen of peripheral blood mononuclear cells and lamina propria lymphocytes has been investigated in normal subjects and patients with inflammatory bowel disease. In the peripheral blood there was reduced antigen induced suppression in patients with Crohn's disease in remission to Mycobacterium ...