BACKGROUND Coexistence of adenocarcinoma and mantle cell lymphoma in the same or different anatomical sites is extremely rare. We present a case of incidental discovery of primary lung adenocarcinoma and mantle cell lymphoma involving the pleura, during an axillary thoracotomy performed for a benign condition. CASE PRESENTATION A 73-year old male underwent bullectomy and apical pleurectomy fo...

The t(14;18)(q32;q21) involving the immunoglobulin heavy chain locus (IGH) and the MALT1 gene is a recurrent abnormality in mucosa-associated lymphoid tissue (MALT) lymphomas. However, the nucleotide sequence of only one t(14;18)-positive MALT lymphoma has been reported so far. We here report the molecular characterization of the IGH-MALT1 fusion products in 5 new cases of t(14;18)-positive MAL...

INTRODUCTION Malignancies of the anal margin and perianal skin are relatively uncommon, and account for approximately 2% to 3% of all anorectal malignancies. Despite the fact that gastrointestinal presentation of lymphoma is not uncommon, primary localization of mantle cell lymphoma to the perianal region is rare. CASE PRESENTATION We present the case of a 64-year-old Turkish man with a rapid...

A classification of chronic (mature) B-cell lymphoproliferative disorders based on reproducible morphologic and immunologic criteria was proposed by the FAB group in 1989. Ever since a number of cytogenetic studies disclosed a remarkable degree of heterogeneity within each disease category. In this table the main cytogenetic entities of chronic lymphocytic leukemia and related disorders, B-cell...

8.1 Deletion in chromosome bands 11q22-q23 in mantle cell lymphoma (study I) ....... 44 8.2 Discontinuous deletion in 11q23 in chronic lymphocytic leukemia (study II). Franssila K, Knuutila S. Gene expression profiling in mantle cell lymphoma and its blastoid variant. Submitted. The publications are referred to by their Roman numerals in the text. 6 2 ABBREVIATIONS BAC bacteria artificial chrom...

..................................................................................................... 10 INTRODUCTION ............................................................................................. 13 REVIEW OF THE LITERATURE ................................................................... 15 EVOLVING CLASSIFICATION OF NON-HODGKIN’S LYMPHOMAS ...................... 15 MANTLE CE...