A series of malignant tumors experimentally induced by implanting Ni3S2 in gelatin capsules into the right hind limb of Fischer 344 rats is described. In this series, histology and ultrastructure revealed two major cell types. These are described as fibroblast-like and histiocyte-like. In addition, numerous giant cells, including large bizarre multinucleate giant cells with granular cytoplasm, ...

Malignant fibrous histiocytoma (MFH) as soft tissue sarcoma would not be especially noteworthy, but primary hepatic MFH reports are extremely rare. Herein, we report ezrin expression in tumor tissues from two primary hepatic MFH cases with different prognoses. Cases 1 and 2 were both women, ages 45 and 70 years, respectively. Case 1 had an 11 x 10 cm liver tumor in segment (S) 3, and case 2 had...

Received 6/29/2006; revised 8/8/2006; accepted 8/10/2006. For correspondence or reprints contact: Cheng-Yi Cheng, M.D., Department of Nuclear Medicine, Tri-Service General Hospital. 325 Section 2, Cheng-Kung Road, Taipei 114, Taiwan, ROC. Tel: (886)2-87927121, Fax: (886)2-87927217, E-mail: [email protected] A 25-year-old young male is a victim of undifferentiated nasopharyngeal carcinoma (NP...

AIMS AND METHODS To study the clinical features, diagnosis, and treatment of primary malignant fibrous histiocytoma of the thyroid (MFH-T). Treatment and outcome were analyzed retrospectively in a consecutive series of 12 patients with primary MFH-T treated at the Cancer Hospital of the Chinese Academy of Medical Sciences from 1987 to 2007. RESULTS All 12 patients underwent surgery; surgery a...

Primary cardiac malignant fibrous histiocytoma is extremely rare and its pathophysiological characteristics remain largely unknown. We treated a female patient with persistent fever and disseminated intravascular coagulation. Since ultrasonic echocardiography revealed the presence of a cardiac tumor and her serum interleukin-6 level was elevated, we speculated she had a cardiac myxoma. Histolog...

BACKGROUND Soft tissue sarcomas in the head and neck region are rare and often present a difficult differential diagnosis. The aim of our presentation is to point out the complexity of the diagnosis, treatment and follow up. CASE PRESENTATION An eighty-seven year old female patient was referred to our unit with a fast growing brownish lump on the face. Four months beforehand, a benign fibrous...

purpose: to report the clinical and histopathological features of recurrent atypical fibrous histiocytoma of the corneo-scleral limbus followed by intra-epithelial squamous neoplasia. case report: a 25-year-old female patient presented with a recurrent vascularized gelatinous mass in the left nasal limbus. the preliminary histopathological diagnosis of the previously excised lesion was an amela...

Although a few cases of sinonasal carcinoma with focal sarcomatous differentiation have been reported, pure sarcomatoid carcinoma has not been reported in the English literature. Imaging studies and gross inspection in a 60-year-old man with left-sided face pain revealed a mass in the left maxillary sinus and nasal cavity. A large incisional biopsy specimen from the nasal cavity revealed prolif...