The male reproductive system consists of the hypothalamus, the anterior pituitary gland, and the testes. Alcohol can interfere with the function of each of these components, thereby causing impotence, infertility, and reduced male secondary sexual characteristics. In the testes, alcohol can adversely affect the Leydig cells, which produce and secrete the hormone testosterone. Studies found that...

Objective: Sex hormones are not only involved in the formation of reproductive organs, but also induce sexually-dimorphic brain development and organization. Cross-sex hormone administration to transsexuals provides a unique possibility to study the effects of sex steroids on brain morphology in young adulthood. Methods: Magnetic resonance brain images were made prior to, and during, cross-sex ...

Background: Lead (Pb) is one of the ubiquitous nonessential haevy metals in the environment. There are evidences, which show that lead toxicity has many undesired effects, including neurological, behavioral, immunological, renal, hepatic, male reproductive, dysfunctions. The objective of the present study was to investigate the effects of aqueous garlic extracts, vitamin E and N-Acetylcysteine ...

Despite male breast cancer is rare in occurrence, it is a serious problem. In 2012, 130 men in Ukraine got breast cancer that constituted 0.74% from all patients with mentioned pathology detected in the course of year. Every year in Ukraine approximately 100 men die from breast cancer. Still many aspects of male breast cancer remain unstudied. It occurs since information about mentioned disease...

In this study, we investigated the effects of ginger and L-carnitine on the reproductive performance of male rats with respect to semen parameters, male sex hormones and the testicular antioxidant system. A total of sixty mature male albino rats were divided into four groups of fifteen rats. The control group received saline, whereas the other three groups received ginger (100 mg kg d 1 .), L-c...

CYP2C11, the most commonly expressed hepatic P450 isoform in male rats, is induced by the masculine “episodic” secretory growth hormone profile. A considerable number of reports have indicated that episodic growth hormone effects are mediated by the activation of the Jak2/Stat5B signal transduction pathway. We observed that restoration of the normal masculine plasma growth hormone pulse in hypo...

OBJECTIVE Insulin downregulates hepatic production of sex hormone-binding globulin (SHBG), which in turn influences sex hormone bioavailability. The effects of childhood-onset diabetes and insulin resistance in nondiabetic individuals on SHBG and testosterone in children and young adults are poorly understood. RESEARCH DESIGN AND METHODS Individuals with diabetes diagnosed at <18 years of age...

The endocrinology of the aging male is complex, with multiple hormones along the hypothalamic-pituitary-testicular (HPT) axis interacting with one another in feedback. As men age, there is a small and progressive (not precipitous, as in women) decline in several sex hormones, in particular testosterone and dehydroepiandrosterone, and related increases in luteinizing hormone, follicle-stimulatin...

The breeding period of Murrels in India is variable. It is well known that environmental cues play an important role in regulating reproduction in teleost fish. Choosing a successful hormone therapy involves the selection of effective hormone formulations, proper duration of hormonal treatment and timing of the hormone administration. Recent advances in chronic hormone delivery vehicle have pro...

Hirsutism is a condition in women that results excessive growth of dark and coarse hair male-like pattern. This very common problem faced by many day-to-day life. often arises from excess male hormones, especially testosterone. Treatment for this includes correcting the underlying hormonal disorder. Although people opt harmful therapies like laser, electrolysis which cause deterioration health....