Glutathione S-transferases (GSTs) are a major family of detoxification enzymes which possess a wide range of substrate specificities. Interest in insect GSTs has primarily focused on their role in insecticide resistance. In this study, following World Health Organization (WHO) routine susceptibility test, DNA was extracted from specimens of Anopheles stephensi collected from the Kazeroon distri...

Malaria is endemic in the North of Brazil. However, Hyperreactive Malarious Splenomegaly (HMS) has been rarely described. Splenomegaly in HIV/Aids infection has a large differential diagnosis, but malaria is a cause of gross splenomegaly, regardless of the HIV status. In this paper, we report the case of a 50-year-old man, HIV positive, with massive splenomegaly and multiple malaria infections ...

Sin,?Mr. Hall, of the Royal Artillery, in the last number of the Gazette, calls attention to the use of strychnine as a substitute for quinine in the treatment of malarious fevers, and " has never yet met with any mention, in books, of this medicine having been given as a substitute for quinine." In the Year Book of the new Sydenham Society for 1862, at page 51, there will be found a record of ...

Abstract Background Sri Lanka sustained its malaria-free status by implementing, among other interventions, three core case detection strategies namely Passive Case Detection (PCD), Reactive (RACD) and Proactive (PACD). The outcomes of these were analysed in terms their effectiveness detecting malaria infections for the period from 2017 to 2019. Methods Comparisons made between surveillance met...

To what extent have weather fluctuations in Africa affected infant mortality over the last fifty years? We investigate this question by combining individual level data, obtained from retrospective fertility surveys (DHS) for more than a million births in 28 African countries, with data for weather outcomes, obtained from re-analysis with climate models (ERA-40). The focus is on two mechanisms: ...

BACKGROUND Artemisinin-based combination treatments (ACTs) are the first-line treatments of uncomplicated Plasmodium falciparum malaria in many endemic areas but there are few evaluation of their efficacy in anaemic malarious children. METHODS Therapeutic efficacy of 3-day regimens of artesunate-amodiaquine and artemether-lumefantrine was evaluated in 437 anaemic and 909 non-anaemic malarious...

Background: According to recent reports during the COVID-19 pandemic, malaria-endemic regions have a significantly lower COVID-19 case and mortality rate than those malaria-non-endemic.  This study aimed to evaluate the prevalence of COVID-19 in malarious areas of southern Iran and the incidence of disease in people previously infected with malaria. Materials and Methods: We conducted an ecolo...