The heterogeneity of a pepsin extract of type-24 M protein (pep M24) was demonstrated by absorption of type-specific and cross-reactive human antisera with M protein fragments and heterologous serotypes of M proteins, pepsin extract of type-5 M protein (pep M5) and pepsin extract of type-6 M protein (pep M6). 2 of 12 individuals immunized with pep M24 developed significant rises in antibody tit...

Synthetic peptides with sequences representing putative transmembrane (M) segments of CFTR (the cystic fibrosis transmembrane conductance regulator) were used as tools to identify the involvement of such segments in forming the ionic pore of the CFTR Cl- channel. Peptides with sequences corresponding to M2 and M6 form anion-selective channels after reconstitution in lipid bilayers. In contrast,...

The spectrometers onboard the Infrared Telescope in Space (IRTS) reveal water vapor absorption in early M-type stars, as early as M2. Previous observations detected H2O vapor absorption only in stars later than M6, with the exception of the recent detection of H2O in β Peg (M2.5 II-III). In our sample of 108 stars, 67 stars have spectral types earlier than M6. The spectral types are established...

The aim of this study was to assess the effects of melatonin on the in vitro maturation and fertilization of sheep oocytes, and on the in vitro culture of the embryos. Oocytes from sheep ovaries collected at the slaughterhouse were divided into four groups, two of which were treated with either 10 M (M5) or 10 M (M6) melatonin, while the other two groups served as untreated controls (C5 and C6)...

Streptococcus pyogenes adheres to human epithelial cells in vitro and in vivo. To identify adhesins, cell wall components were extracted from S. pyogenes M6 with alkali or by treatment with mutanolysin and lysozyme. HEp-2 cells were incubated with extracts of S. pyogenes M6 and then analyzed by Western blot (immunoblot) assays, using antibodies to S. pyogenes. Only one streptococcal component (...

The information loss paradox for Schwarzschild black holes is examined, using the ADS/CFT correspondence extended to the M6(4, 2) bulk. It is found that the only option compatible with the preservation of the quantum unitarity is when a regular remnant region of the black hole survives to the black hole evaporation process, where information can be stored and eventually retrieved. The ADS/CFT C...

The generalized penetration depth PD of two overlapping bodies X and Y is the distance between the given colliding position of X and the closest collision-free Euclidean copy Xε to X according to a distance metric. We present geometric optimization algorithms for the computation of PD with respect to an object-oriented metric S which takes the mass distribution of the moving body X into conside...

Extracellular matrix metalloproteinase inducer (EMMPRIN) is a human leukocyte surface molecule that is enriched on the surface of many cancer cells, and it plays an important role in proliferation and metastasis. In this study, we utilized the chimeric adenoviral vector Ad5/F35 carrying gene encoding scFv against EMMPRIN (scFv-M6-1B9) to down-regulate EMMPRIN cell surface expression and investi...

Psoralen (pso) was attached via its C-5 position to the 5'-phosphate group of an oligodeoxynucleotide d(TAAGCCG) by a hexamethylene linker (m6). Complex formation between pso-m6-d(TAAGCCG) and the complementary strands d(CGGCTTA)[7-7mer] or d(CGGCTTAT)[7-8mer] was investigated by nuclear magnetic resonance in aqueous solution. Structural informations derived from DQF-COSY and NOESY maps, reveal...

In the August 1,1991 issue ofBlood, San Miguel et all published a report of 41 acute leukemia cases secondary to a myelodysplastic syndrome (MDS). Two were classified as M6 French-AmericanBritish (FAB) subtype on morphologic aspect, but the only erythroid immunologic marker tested, ie, glycophorin A, was negative. This characteristic, owing to the fact that glycophorin A is a relatively mature ...