نتایج جستجو برای: lymphoma therapy
تعداد نتایج: 741717 فیلتر نتایج به سال:
background: the fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.the high linear energy transfer (let) of alpha radiation to the targeted cancer cellscauses double strand breaks in dna. at the same time, the short range radiation spares adjacent normal tissues. this targeted approach complements conventional external beam radiotherapy and ch...
The standard management of low-grade lymphoma remains controversial. Long-term follow-up studies of patients treated with conventional regimens have shown that currently available treatments are not curative. New Treatment Approaches for Low-Grade Lymphoma Nucleoside AnalogsNewer chemotherapeutic agents, such as fludarabine (Fludara) and cladribine (2-chlorodeoxyadenosine [Leustatin]), have si...
BACKGROUND Positron emission tomography (PET) is more accurate than computed tomography (CT) in staging and restaging of lymphoma, but both are considered necessary. Increasingly, PET is carried out with a low-dose CT scan. Many patients undergo both PET/CT and standard diagnostic CT. The clinical utility of performing both studies in patients with lymphoma was evaluated. PATIENTS AND METHODS...
In recent years, the number of approved and investigational agents that can be safely administered for the treatment of lymphoma patients for a prolonged period of time has substantially increased. Many of these novel agents are evaluated in early-phase clinical trials in patients with a wide range of malignancies, including solid tumors and lymphoma. Furthermore, with the advances in genome se...
Although the GI tract is the most common site of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT),1,2 duodenal MALT lymphoma is rare.3-10 The eradication of Helicobacter pylori is now considered the treatment of choice for gastric MALT lymphoma,11-14 yet therapeutic strategies for duodenal MALT lymphoma are still in dispute.3-10 This is a report of 2 cases of duodenal MALT ...
In the last years several borderline B-cell lymphoid proliferations have been recognized that lie at interface between benign and malignant. These lesions can be divided in two groups; those considered precursor of well malignancies group indolent lymphomas with limited potential for progression. Precursor are monoclonal share many genetic features their malignant counterpart. The first lesion ...
Nodular lymphocyte predominant Hodgkin lymphoma appears in 5% of lymphoma. Because major biological and clinical differences with classical close relationship to T-cell/histiocyte-rich large B-cell lymphoma, lately the term nodular is accepted. The presence cells preserved phenotype a lack CD30 prerequisite for diagnosis Lymphocyte are typically embedded nodules B lymphocytes (growth patterns A...
Background: The effectiveness of treatment with antibiotic for mucosa-associated lymphoid tissue (MALT) lymphoma in the stomach has been widely recognized in the last few decades. On the other hand, MALT lymphoma of the rectum is rare, and some literature has reported the usefulness of eradication of Helicobacter pylori, but the standard method of treatment has not been established. Case presen...
Delivery of cytotoxic agents specifically to malignant cells has always been a goal of cancer therapy. With the development of monoclonal antibodies for clinical use, this goal has become a reality, and antibody-drug conjugates are now part of standard therapy in diseases such as lymphoma and breast cancer. Brentuximab vedotin, which targets CD30, has contributed to the success of antibody-drug...
T-cell lymphoma is a heterogeneous group of diseases. Except for ALK positive anaplastic large cell lymphoma, T-cell lymphoma responds to conventional chemotherapy unfavourably, and most patients carry poor prognosis. In recent years, efforts have been made to improve the outcome of T-cell lymphoma patients. Novel agents, high-dose therapy, and allogeneic stem cell transplantation are studied, ...
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