نتایج جستجو برای: lymphocyte responses

تعداد نتایج: 446617  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1979
J A McIntyre W P Faulk

Human syncytiotrophoblast cell membranes prepared by differential ultracentrifugation were extracted with 3 M KCl, solubilized in 1% deoxycholate, and chromatographically separated into two peaks by passage through a column of Bio-Gel P-200. Previous reports from this laboratory have shown that the first peak (PI) is serologically the same as a group of trophoblast membrane antigens tentatively...

Farzaneh Pourasgari Fatemeh Rahbarizadeh Fereidoun Mahboudi, Hamidreza Korram Khorshid Haydeh Darabi Kayhan Azadmanesh Masoumeh Ebtekar, Mehdi Mahdavi Zuhair Mohammad Hassan

Background: Cell mediated immunity, especially cytotoxic T cell responses against HIV-1 infection, plays a critical role in controlling viral replication and disease progres-sion. DNA vaccine is a novel technology which is known to stimulate strong cellular immune responses. Many DNA vaccines have been tested for HIV infection but there is still no effective vaccine against this infection. Cons...

2011
Tatenda Mahlokozera Helen H. Kang Nilu Goonetilleke Andrea R. Stacey Rachel V. Lovingood Thomas N. Denny Linda Kalilani James E. G. Bunn Steve R. Meshnick Persephone Borrow Norman L. Letvin Sallie R. Permar

BACKGROUND The risk of postnatal HIV transmission is associated with the magnitude of the milk virus load. While HIV-specific cellular immune responses control systemic virus load and are detectable in milk, the contribution of these responses to the control of virus load in milk is unknown. METHODS We assessed the magnitude of the immunodominant GagRY11 and subdominant EnvKY9-specific CD8+ T...

Journal: :Annals of the rheumatic diseases 1976
S Pugh B Pelton E B Raftery A M Denman

Abnormal lymphocyte function has been frequently reported in patients with connective tissue diseases but its significance has been uncertain. Sequential studies of lymphocyte function were carried out in patients receiving the beta-adrenergic blocking drug practolol (Eraldin) both before and during the development of autoimmune complications. No evidence was obtained that abnormal lymphocyte f...

Cancer immunotherapy has gained a lot of interest over the past few years due to the success of immune checkpoint inhibitors in treating cancer (1, 2). Immune checkpoint inhibitors, such as monoclonal antibodies against cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) and programmed death 1 (PD-1), have been shown to increase survival of patients with advanced cancers (1, 2). These in...

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