ABSTRACT: Leishmania infantum causes canine leishmaniasis. Using parasitological and molecular analyses, we identified L. in the reproductive organs of male female dogs. histochemistry, immunohistochemistry, PCR, examined tissue samples from 8 dogs 16 diagnosed with Despite absence macroscopic or microscopic lesions these organs, observed amastigotes testis uterus. PCR sequencing tissues reveal...

Visceral leishmaniasis, in Greece, represents a relatively rare, potentially fatal clinical entity. Here we describe a case of visceral leishmaniasis infection in a 65-year old Greek male with psoriatic arthritis treated with methotrexate, who presented with high grade fever, chills, splenomegaly, pancytopenia and polyclonal hypergammaglobulinaemia. A diagnosis of visceral leishmaniasis was fin...

The wide variety of Leishmania species responsible for human American cutaneous leishmaniasis combined with the immune mechanisms of the host results in a large spectrum of clinical, histopathological, and immunopathological manifestations. At the middle of this spectrum are the most frequent cases of localized cutaneous leishmaniasis (LCL) caused by members of the subgenera Leishmania and Vian...

BACKGROUND The number of leishmaniasis cases associated with immunosuppression has increased regularly over the past 20 years. Immunosuppression related to HIV infection, immunosuppressive treatment, organ transplantation, and neoplastic diseases increases the risk for Leishmania-infected people to develop visceral illness. CASE PRESENTATION Three cases of Leishmania infantum leishmaniasis in...

Systemic lupus Erythematosus (SLE) is a chronic inflammatory disease that affects multiple organs and systems such as skin, joints, kidneys, cardiovascular and central nervous systems. Twenty five to fifty percent of the patients with the diagnosis of SLE develop abnormal liver test during the course of the disease, being the main causes: hepatotoxic drugs, viral hepatitis and fatty liver disea...

Leishmaniasis is a group of diseases caused by the protozoa Leishmania, endemic in the Mediterranean countries. Clinical manifestations can be divided into three different forms: cutaneous leishmaniasis, mucosal leishmaniasis and the visceral leishmaniasis, the most severe form which is potentially lethal if untreated. Immunology and pathogenesis are complex: many different aspects of immune re...

INTRODUCTION .......................................................................................................................................................229 Clinical Leishmaniasis ...........................................................................................................................................229 Self-limiting cutaneous and visceral leishmaniasis ...............

INTRODUCTION .......................................................................................................................................................229 Clinical Leishmaniasis ...........................................................................................................................................229 Self-limiting cutaneous and visceral leishmaniasis ...............

Leishmaniasis is caused by the infection of haemoparasite „Leishmaniadonovani’. Clinically it can present as Cutaneous Leishmaniasis (CL), Mucocutaneous Leishmaniasis (MCL) and Visceral Leishmaniasis (VL). In India it is a major health problem in the North & Central regions of India and is infrequently reported from western India. However, we encountered two clinically suspected cases of Leishm...

Leishmaniasis is a disease caused by protozoa of the genus Leishmania, and visceral leishmaniasis is a form in which the inner organs are affected. Since knowledge about immunity in experimental visceral leishmaniasis is poor, we present here a review on immunity and immunosuppression in experimental visceral leishmaniasis in mouse and hamster models. We show the complexity of the mechanisms in...