garbage collectors are occupationally exposed to a variety of airborne contaminants. the main objective of this study was to evaluate the respiratory health of garbage collectors. this study was carried out in fars province, south of iran. a group of 105 garbage collectors and 93 referent subjects were investigated. a standard questionnaire was administered to both groups. furthermore, subjects...

background: imatinib mesylate is the first generation of tyrosine kinase inhibitors (tki) and highly effective in the treatment of chronic myeloid leukemia (cml). we aimed to evaluate thyroid function at baseline and at 1, 3, 6 and 12 months after initiation of imatinib mesylate therapy in 20 newly diagnosed bcr-abl positive cml patients. methods: this study was done during 2013-2014, 20 new ca...

background: sickle-cell disease (scd) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. cardiovascular events and complications are the leading cause of mortality and morbidity in patients with scd. tissue doppler imaging and the myocardial performance index (tei index), are simple indices for the assessment of the cardiac f...

background and objective: hypothyroidism is a known consequence of the external beam radiotherapy to the neck encompassing the thyroid gland for over 40 years. the aim of this study was to find out the incidence of hypothyroidism in patients with head and neck cancer treated with radiotherapy, when radiation portals included whole of the thyroid gland. materials and methods: this prospective no...

conclusions aed improved liver enzymes in obese women. however, mild, transient increases in alt and ast values can be observed immediately after an nfd in women. results of 108 participants, 50 women in aed group and 50 women in nfd group completed the protocol of the study (response rate: 92.6 %). the aed led to a median weight loss of 3.79 kg (interquartile range: 4.4 kg). significant decrea...

background: several studies have showed an increased prevalence of airflow obstruction in first degree relatives of individuals with chronic obstructive pulmonary disease (copd). considering no specific research had evaluated airway resistance in offspring of patients with severe copd, we utilized a spirometry and a impulse oscillometry (io) to evaluate this population. materials and methods: i...

BACKGROUND AND OBJECTIVE It is currently recommended that patients avoid large meals prior to their lung function tests. The aim of this study is to determine whether this recommendation is necessary in clinical practice. METHODS A randomized controlled cross-over trial was conducted. Subjects performed lung function tests (spirometry, measurement of lung volumes and gas transfer) prior to, d...

The lung is the primary organ likely to be exposed by inhalation studies and, therefore, measurement of changes in lung function are of particular interest to the pulmonary physiologist and toxicologist. Tests of pulmonary function have been developed which can be used with small animals to measure spirometry (lung volumes), mechanics, distribution of ventilation, gas exchange or control of ven...

AIMS To determine the association between lung function of coke oven workers and exposure to coke oven emissions. METHODS Lung function data and detailed work histories for workers in recovery coke ovens of a steelworks were extracted from a lung function surveillance system. Multiple regressions were employed to determine significant predictors for lung function indices. The first sets of lu...