Photostimulated luminescence (PSL) and thermoluminescence (TL) from five L~2(1-~)Ce2~(Si04)0 &SO) crystals with different light outputs is reported. Optical irradiation into the Ce3+ absorption bands causes the appearance of a broad absorption band near 280 nm which is ascribed to Ce4+. In addition, a tail is observed extending beyond 700 nm. Optical irradiation into this tail (PSL) or heating ...

Glycine and GABA, the dominant inhibitory neurotransmitters in the CNS, assume a depolarizing role in early development, leading to increased cytoplasmic Ca2+ levels and action potentials. The effect is thought to be of some significance for maturation. The depolarization is caused by Cl- efflux, and chloride transporters contribute to the phenomenon by raising the intracellular Cl- concentrati...

The lateral superior olive (LSO) is one of the earliest sites in the auditory pathway involved in processing acoustical cues to sound location. LSO neurons encode the interaural level difference (ILD) cue to azimuthal location. Here we investigated the effect of variations in the overall stimulus levels of sounds at the two ears on the sensitivity of LSO neurons to small differences in ILDs of ...

The interaural level difference (ILD) cue to sound location is first encoded in the lateral superior olive (LSO). ILD sensitivity results because the LSO receives excitatory input from the ipsilateral cochlear nucleus and inhibitory input indirectly from the contralateral cochlear nucleus via glycinergic neurons of the ipsilateral medial nucleus of the trapezoid body (MNTB). It is hypothesized ...

background: health status of offspring is programmed by maternal diet throughout gestation and lactation. the present study investigates the lasting effects of maternal supplementation with different amounts of soy oil or extra virgin olive oil (evoo) on weight and biochemical parameters during gestation and lactation of female mice offspring. methods: eight weeks old female c57bl/6 mice (n=40)...

Damaging levels of sound (acoustic trauma, AT) diminish peripheral synapses, but what is the impact on the central auditory pathway? Developmental maturation of synaptic function and hearing were characterized in the mouse lateral superior olive (LSO) from P7 to P96 using voltage-clamp and auditory brainstem responses (ABR). IPSCs and EPSCs show rapid acceleration during development, so that de...

Within the Ca(v)1 family of voltage-gated calcium channels, Ca(v)1.2 and Ca(v)1.3 channels are the predominant subtypes in the brain. Whereas specific functions for each subtype were described in the adult brain, their role in brain development is poorly understood. Here we assess the role of Ca(v)1.3 subunits in the activity-dependent development of the auditory brainstem. We used Ca(v)1.3-def...

In the lateral superior olive (LSO) the firing rate of principal neurons is a linear function of inter-aural sound intensity difference (IID). The linearity and regularity of the "chopper response" of these neurons have been interpreted as a result of an integration of excitatory ipsilateral and inhibitory contralateral inputs by passive soma-dendritic cable properties. To account for temporal ...